Galarza Carlos, Gutiérrez Ericson L, Ramos Willy, Tello Mercedes, Ronceros Gerardo, Alvizuri Sergio, Valverde Filda, Ortega-Loayza Alex G
instituto de Investigaciones Clínicas, Universidad Nacional Mayor de San Marcos, Lima, Perú
Rev Med Chil. 2009 Sep;137(9):1205-8.
Endemic pemphigus foliaceus (EPF) in an autoimmune skin disease present in areas of the Amazonia. We report a 36 year-old woman who presented EPF at 17 weeks of pregnancy. At 29 weeks, she started antimicrobial treatment and steroids. At the moment of delivery, the disease was in remission and cutaneous lesions were not seen in the neonate. Indirect immunofluorescence titers of total IgG in the mother and in the neonate were negative. Sixteen months later, IgG titers in the offspring were 1/20 and remained negative in the mother, who was on low doses of oral corticosteroids.
地方性落叶型天疱疮(EPF)是一种自身免疫性皮肤病,见于亚马逊地区。我们报告一名36岁女性,在妊娠17周时出现EPF。29周时,她开始接受抗菌治疗和使用类固醇。分娩时,疾病处于缓解期,新生儿未见皮肤病变。母亲和新生儿的总IgG间接免疫荧光滴度均为阴性。16个月后,后代的IgG滴度为1/20,母亲的滴度仍为阴性,母亲正在服用低剂量口服皮质类固醇。