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[妊娠期天疱疮。一例病例报告及文献综述]

[Pemphigus in pregnancy. A case report and literature review].

作者信息

Solís-Arias Martha Patricia, Lammoglia-Ordiales Lorena, Vega-Memije María Elisa

出版信息

Ginecol Obstet Mex. 2014 Jan;82(1):64-9.

Abstract

Pemphigus vulgaris is a bullous, autoimmune, mucocutaneous and potentially fatal disease. Association between pemphigus vulgaris and pregnancy is little frequent. Evolution of this autoimmune disease is different, because of the hormone and immunological disorders related to pregnancy. Adverse effects on fetus should be taken into account, by drugs administered to the mother and by the transference of antibodies by transplacentary route. This paper reports the case of a 21-year-old female patient with diagnosis of pemphigus vulgaris since 14 years old, who assisted to consultation due to a pregnancy of three-months and exacerbation of the disease.

摘要

寻常型天疱疮是一种大疱性、自身免疫性、皮肤黏膜疾病,可能致命。寻常型天疱疮与妊娠之间的关联并不常见。由于与妊娠相关的激素和免疫紊乱,这种自身免疫性疾病的病程有所不同。应考虑到母亲所服用药物以及抗体经胎盘途径转移对胎儿产生的不良影响。本文报告了一名21岁女性患者的病例,该患者自14岁起被诊断为寻常型天疱疮,因怀孕三个月且病情加重前来就诊。

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