Román A Oscar, Prieto C María José, Mancilla F Pedro, Astudillo O Pedro, Dussaubat A Ana María, Miguel W Carolina, Lara M Jennifer
Unidad de Salud Respiratoria, Ministerio de Salud, Chile.
Rev Med Chil. 2009 Sep;137(9):1217-24.
A clear cut relationship between particulate matter air contamination and the mortality and morbidity due to respiratory disease has been observed in the last decades. However there is also a relationship between air pollution and cardiovascular diseases. In big cities, a big or small particle concentration increase of 10 micro/m(3) is associated with a significantly higher risk of ischemic heart disease and myocardial infarction, both when acute or chronic exposures are considered. The risk is higher for small particles. Similar risk increases are observed in patients with hypertension, stroke or severe arrhythmias. This association is independent of environmental distracters such as weather, temperature or humidity and of classical cardiovascular risk factors such as age, diabetes, dyslipidemia and obesity. Physicians should be aware of the problem and explain their patients the increased risk that they are facing due to air pollution.
在过去几十年中,已观察到空气中的颗粒物污染与呼吸系统疾病导致的死亡率和发病率之间存在明确的关系。然而,空气污染与心血管疾病之间也存在关联。在大城市中,无论是考虑急性暴露还是慢性暴露,空气中小颗粒或大颗粒浓度每增加10微克/立方米,患缺血性心脏病和心肌梗死的风险就会显著升高。小颗粒导致的风险更高。在高血压、中风或严重心律失常患者中也观察到类似的风险增加。这种关联独立于天气、温度或湿度等环境干扰因素,以及年龄、糖尿病、血脂异常和肥胖等经典心血管危险因素。医生应该意识到这个问题,并向患者解释由于空气污染他们所面临的风险增加。