Windischberger C, Fischmeister F P S, Schöpf V, Sladky R, Moser E
Exzellenzzentrum Hochfeld-MR, Medizinische Universität Wien, Lazarettgasse 14, A-1090, Wien, Osterreich.
Radiologe. 2010 Feb;50(2):144-51. doi: 10.1007/s00117-009-1897-9.
Functional magnetic resonance imaging (fMRI) is currently the primary method for non-invasive functional localization in the brain. With the emergence of MR systems with field strengths of 4 Tesla and above, neuronal activation may be studied with unprecedented accuracy. In this article we present different approaches to use the improved sensitivity and specificity for expanding current fMRT resolution limits in space and time based on several 7 Tesla studies. In addition to the challenges that arise with ultra-high magnetic fields possible solutions will be discussed.
功能磁共振成像(fMRI)是目前用于大脑非侵入性功能定位的主要方法。随着场强为4特斯拉及以上的磁共振系统的出现,可以以前所未有的精度研究神经元激活。在本文中,我们基于几项7特斯拉的研究,介绍了不同的方法,利用提高的灵敏度和特异性来扩展当前功能磁共振成像在空间和时间上的分辨率极限。除了超高磁场带来的挑战外,还将讨论可能的解决方案。