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蝙蝠相关的钩端螺旋体病。

Bat-associated leptospirosis.

机构信息

Department of Medicine, Northwestern University Feinberg School of Medicine, 251 E Huron St, Galter 3-150, Chicago, IL 60611, USA.

出版信息

J Gen Intern Med. 2010 Feb;25(2):162-4. doi: 10.1007/s11606-009-1210-7. Epub 2009 Dec 9.

Abstract

Leptospirosis is a globally prevalent disease that affects humans, causing systemic illness that may lead to multi-organ involvement. Clinical signs include sudden fever, general malaise, muscular pain, conjunctival suffusion, and jaundice. Disease is caused by pathogenic bacteria including over 200 serologic variants. Most serologic variants have primary reservoirs in wild mammals, which continually infect and colonize domesticated animals. The organism has been recovered from rats, swine, dogs, cattle, and other animals, notably bats. Most studies have focused on domestic animals as reservoir hosts; however, because of their abundance, spatial distribution, and interrelationship with domestic animals, bats are becoming an epidemiologically significant source of leptospires. We present a case of serologically confirmed leptospirosis after bat exposure to add to the growing literature of bats as a possible source of transmission. Recognition of the common presentation of leptospirosis and Weil's disease, and identification of animal vectors, including bats, allows for the selection of appropriate antibiotic management to aid in resolution of symptomotology.

摘要

钩端螺旋体病是一种全球性流行疾病,影响人类,引起全身性疾病,可能导致多器官受累。临床症状包括突发高热、全身不适、肌肉疼痛、结膜充血和黄疸。该病由包括 200 多种血清型变异体在内的致病性细菌引起。大多数血清型变异体的主要宿主是野生动物,它们不断感染和定殖于家养动物。该病原体已从老鼠、猪、狗、牛和其他动物,特别是蝙蝠中分离出来。大多数研究都集中在家畜作为储存宿主上;然而,由于蝙蝠数量多、空间分布广,且与家畜相互关系密切,它们已成为钩端螺旋体病的一个具有流行病学意义的重要来源。我们报告了一例经蝙蝠接触后血清学确认的钩端螺旋体病,以增加有关蝙蝠可能作为传播源的不断增长的文献。认识到钩端螺旋体病和韦尔氏病的常见表现,并识别出动物载体,包括蝙蝠,有助于选择适当的抗生素治疗,以帮助缓解症状。

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