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[钩端螺旋体感染鼠群可能是韦尔病致死病例的病因]

[Leptospira infected rat population as probable cause of a fatal case of Weil's disease].

作者信息

Brem S, Radu O, Bauer T, Schönberg A, Reisshauer K, Waidmann R, Kopp H, Meyer P

机构信息

LUA Oberschleissheim.

出版信息

Berl Munch Tierarztl Wochenschr. 1995 Nov;108(11):405-7.

PMID:8593131
Abstract

In the summer of 1992 a patient died of a leptospiral infection which he probably had contracted while he was swimming in an artificial lake in the region of Tübingen/Reutlingen. Regarding the epidemiological role of leptospirosis the rodent population was investigated, because rats and mice were often seen in the surrounding area. 11 rats and 20 mice could be trapped. From their urine or kidneys two leptospiral serovars were isolated: Serovar copenhageni from Rattus norvegicus and serovar saxkoebing from Clethrionomys glareolus. Leptospiral antibody titers were not detected in one of these infected animals. It may be supposed that the Leptospira interrogans serovar copenhageni out of the Serogroup Icterohaemorrhagiae had caused the leptospiral infection of the patient.

摘要

1992年夏天,一名患者死于钩端螺旋体感染,他很可能是在图宾根/罗伊特林根地区的人工湖游泳时感染的。考虑到钩端螺旋体病的流行病学作用,对啮齿动物种群进行了调查,因为在周边地区经常能看到大鼠和小鼠。捕获了11只大鼠和20只小鼠。从它们的尿液或肾脏中分离出两种钩端螺旋体血清型:从褐家鼠中分离出哥本哈根血清型,从林姬鼠中分离出萨克森血清型。在其中一只受感染的动物中未检测到钩端螺旋体抗体滴度。可以推测,出血热群中的问号钩端螺旋体哥本哈根血清型导致了该患者的钩端螺旋体感染。

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