Baker G B, Bornstein R A, Rouget A C, Ashton S E, van Muyden J C, Coutts R T
PMHAC Research Unit, University of Alberta, Edmonton, Canada.
Biol Psychiatry. 1991 Jan 1;29(1):15-22. doi: 10.1016/0006-3223(91)90207-3.
Urinary excretion (24-hr) of beta-phenylethylamine (PEA), phenylacetic acid (PAA), phenylalanine (Phe), and p-tyrosine (Tyr), and plasma levels of PAA, Phe, and Tyr were examined in 18 normal children and 26 children diagnosed as having attention-deficit hyperactivity disorder (ADHD). The results indicated that urinary excretion (expressed per g of creatinine) of free and total PEA was significantly lower in the ADHD patients, and plasma levels of Phe and Tyr were also decreased in the ADHD subjects compared with the normal controls.
对18名正常儿童和26名被诊断为注意力缺陷多动障碍（ADHD）的儿童进行了β-苯乙胺（PEA）、苯乙酸（PAA）、苯丙氨酸（Phe）和对酪氨酸（Tyr）的24小时尿排泄量检测，以及PAA、Phe和Tyr的血浆水平检测。结果表明，ADHD患者中游离和总PEA的尿排泄量（以每克肌酐表示）显著降低，与正常对照组相比，ADHD受试者的Phe和Tyr血浆水平也有所下降。
