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骨骼肌损伤与衰老适应:对复杂范式的新见解。

Skeletal muscle injury versus adaptation with aging: novel insights on perplexing paradigms.

机构信息

National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States.

出版信息

Exerc Sport Sci Rev. 2010 Jan;38(1):10-6. doi: 10.1097/JES.0b013e3181c5cd7c.

DOI:10.1097/JES.0b013e3181c5cd7c
PMID:20016294
Abstract

A growing body of data supports a view that skeletal muscle's response after mechanical loading does not always result in the classically reported "injury response." Furthermore, current evidence supports a model of muscle adaptation and/or maladaptation, distinct from overt injury, in which myofiber degeneration and inflammation do not contribute as significantly as once reported even in aged populations.

摘要

越来越多的数据支持这样一种观点,即骨骼肌在机械负荷后的反应并不总是导致经典报道的“损伤反应”。此外,目前的证据支持一种不同于明显损伤的肌肉适应和/或适应不良的模型,即使在老年人群中,肌纤维变性和炎症的贡献也不像以前报道的那样大。

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