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长期接触常见垫料对雄性CD-1小鼠代谢率和整体健康的影响。

The effects of chronic exposure to common bedding materials on the metabolic rate and overall health of male CD-1 mice.

作者信息

Becker Corey E, Mathur Carolyn F, Rehnberg Bradley G

机构信息

Department of Biological Sciences, York College of Pennsylvania, York, PA 17405-7199, USA.

出版信息

J Appl Anim Welf Sci. 2010;13(1):46-55. doi: 10.1080/10888700903372010.

DOI:10.1080/10888700903372010
PMID:20017045
Abstract

Anecdotes and personal Web pages claim that cedar and pine beddings cause respiratory distress in rodents, although no previous research could be found to support these claims. There have, however, been published studies of respiratory distress in cedar and pine mill workers. That research links exposure to wood dust to asthma and to bronchial and alveolar damage in humans. This study looks at the effects of 3 types of bedding (CareFRESH Original, cedar, and pine) on the growth, food intake, oxygen consumption, IgE antibody concentrations, and general appearance and behavior in male CD-1 mice. Mice who were housed on these beddings for approximately 4 months did not show significant differences in any of these variables. This suggests that these 3 materials provide equally healthy substrates for long-term rearing of mice and possibly other rodents.

摘要

轶事和个人网页称雪松和松木垫料会导致啮齿动物呼吸窘迫,不过此前未找到支持这些说法的研究。然而,已有关于雪松和松木加工厂工人呼吸窘迫的研究发表。该研究将接触木屑与人类哮喘以及支气管和肺泡损伤联系起来。本研究观察了三种垫料(CareFRESH原味垫料、雪松和松木)对雄性CD-1小鼠的生长、食物摄入量、耗氧量、IgE抗体浓度以及总体外观和行为的影响。在这些垫料上饲养约4个月的小鼠在这些变量中均未表现出显著差异。这表明这三种材料为长期饲养小鼠以及可能的其他啮齿动物提供了同样健康的垫料。

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J Appl Anim Welf Sci. 2010;13(1):46-55. doi: 10.1080/10888700903372010.
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