Zimin A A, Zhevago N A, Buĭniakova A I, Samoĭlova K A
Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Nov-Dec(6):49-52.
Although low-power visible (VIS) and near infrared (nIR) radiation emitted from lasers, photodiodes, and other sources does not cause neoplastic transformation of the tissue, these phototherapeutic techniques are looked at with a great deal of caution for fear of their stimulatory effect on tumour growth. This apprehension arises in the first place from the reports on the possibility that the proliferative activity of tumour cells may increase after their in vitro exposure to light. Much less is known that these phototherapeutic modalities have been successfully used for the prevention and management of complications developing after surgery, chemo- and radiotherapy. The objective of the present review is to summarize the results of applications of low-power visible and near infrared radiation for the treatment of patients with oncological diseases during the last 20-25 years. It should be emphasized that 2-4 year-long follow-up observations have not revealed any increase in the frequency of tumour recurrence and metastasis.
尽管激光、光电二极管及其他光源发出的低功率可见光(VIS)和近红外(nIR)辐射不会导致组织发生肿瘤转化,但由于担心其对肿瘤生长的刺激作用,这些光疗技术仍受到高度谨慎对待。这种担忧首先源于有关肿瘤细胞在体外暴露于光后增殖活性可能增加的报道。而对于这些光疗方式已成功用于预防和处理手术、化疗及放疗后出现的并发症,人们了解得要少得多。本综述的目的是总结过去20至25年间低功率可见光和近红外辐射在肿瘤疾病患者治疗中的应用结果。应当强调的是,长达2至4年的随访观察并未发现肿瘤复发和转移频率有任何增加。