Panizzi Luca, Barber Spencer M, Lang Hayley M, Carmalt James L
Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Canada.
Vet Surg. 2009 Dec;38(8):998-1005. doi: 10.1111/j.1532-950X.2009.00589.x.
To describe signalment, clinical, and radiographic changes associated with carpometacarpal osteoarthritis (CMC-OA) and to report long-term outcome.
Case series.
Horses (n=33) with CMC-OA.
Medical records (1992-2007) of horses diagnosed with CMC-OA were reviewed and signalment, clinical, and radiographic findings retrieved. Owners were contacted for information on the impact of lameness on intended use, response to treatment, progression of lameness, outcome, and owner satisfaction with response to treatment.
CMC-OA identified in 39 limbs, occurred predominantly in middle-aged and older Quarter Horses and Arabians, and caused severe lameness that prevented normal use. Characteristic swelling was centered over the 2nd metacarpal bone/2nd carpal bone articulation. Radiographic changes consisted of proliferative new bone, narrowed joint space, and subchondral lysis. Of 20 horses with follow-up, 7 of 14 treated horses were euthanatized within 4 years and 4 of 5 nontreated horses within 3 years. Response to treatment was short lived and considered very poor by most owners.
CMC-OA seemingly occurs primarily in Quarter Horses and Arabians in our region. Response to conservative treatment is very poor and short-lived with most horses being euthanatized.
Conventional treatment methods are unsuccessful for treating CMC-OA.
描述与腕掌关节骨关节炎（CMC - OA）相关的体征、临床及影像学变化，并报告长期预后情况。
病例系列研究。
患有CMC - OA的马（n = 33）。
回顾1992 - 2007年被诊断为CMC - OA的马的病历，获取体征、临床及影像学检查结果。联系马主，了解跛行对预期用途的影响、对治疗的反应、跛行进展、预后以及马主对治疗反应的满意度等信息。
在39个肢体中发现CMC - OA，主要发生在中年及老年的夸特马和阿拉伯马，导致严重跛行，使其无法正常使用。特征性肿胀集中在第二掌骨/第二腕骨关节处。影像学变化包括增生性新骨、关节间隙变窄和软骨下溶解。在20匹有随访记录的马中，14匹接受治疗的马中有7匹在4年内实施安乐死，5匹未接受治疗的马中有4匹在3年内实施安乐死。治疗反应持续时间短，大多数马主认为治疗效果很差。
在我们地区，CMC - OA似乎主要发生在夸特马和阿拉伯马。保守治疗反应很差且持续时间短，大多数马最终被实施安乐死。
传统治疗方法对治疗CMC - OA无效。
