Faculty of Nutrition, School of Public Health, Sun Yat-sen University, Guangzhou, China.
Public Health Nutr. 2010 Oct;13(10):1546-52. doi: 10.1017/S1368980009992849. Epub 2009 Dec 17.
The estimation of dietary intake in population-based studies is often assessed by the FFQ. The objective of our study is to evaluate the validity of an FFQ used to assess dietary fatty acid intake among middle-aged Chinese adults in Southern China.
The method of triads was applied to obtain the validity coefficients (VC) of the FFQ for specific fatty acids. A subsample was randomly selected from an earlier cross-sectional study. The FFQ and 3d dietary records were used for dietary assessment, and the fatty acid composition of erythrocyte membranes was determined as the biomarker.
The Spearman correlation coefficients between the FFQ and 3d dietary records were moderate to good (r = 0.28-0.66). The VC of the FFQ estimated by the method of triads were 0.72, 0.61, 0.65, 0.75 and 0.67 for MUFA, total n-6 fatty acids, alpha-linolenic acid, EPA and DHA, respectively. The VC could not be calculated for SFA, PUFA and total n-3 fatty acids because of negative correlations among the three measurements. But, the correlations between the FFQ and the dietary records were moderate for these fatty acids.
Our FFQ applied in Southern Chinese adults was valid to estimate their dietary fatty acid intake and was thus suitable for use in a large cohort study.
在基于人群的研究中，通常通过 FFQ 来评估膳食摄入量。本研究旨在评估一种用于评估中国南方中年人群膳食脂肪酸摄入量的 FFQ 的有效性。
采用三组合法获得 FFQ 对特定脂肪酸的有效性系数 (VC)。从早期的横断面研究中随机抽取一个亚样本。使用 FFQ 和 3 天饮食记录进行饮食评估，并确定红细胞膜的脂肪酸组成作为生物标志物。
FFQ 与 3 天饮食记录之间的 Spearman 相关系数为中度至良好 (r = 0.28-0.66)。三组合法估计的 FFQ 的 VC 分别为 0.72、0.61、0.65、0.75 和 0.67，用于 MUFA、总 n-6 脂肪酸、α-亚麻酸、EPA 和 DHA。由于三种测量方法之间存在负相关，因此无法计算 SFA、PUFA 和总 n-3 脂肪酸的 VC。但是，对于这些脂肪酸，FFQ 与饮食记录之间的相关性为中度。
我们应用于中国南方成年人的 FFQ 能够有效评估他们的膳食脂肪酸摄入量，因此适合用于大型队列研究。
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