Cohen P R, Held J L, Grossman M E, Ross M J, Silvers D N
Department of Dermatology, College of Physicians and Surgeons of Columbia University, New York, New York.
Int J Dermatol. 1991 Feb;30(2):104-8. doi: 10.1111/j.1365-4362.1991.tb04220.x.
A 46-year-old homosexual man with disseminated histoplasmosis and human immunodeficiency virus (HIV) infection had a histoplasmosis-related ulcerated verrucous plaque above his left upper lip; systemic and cutaneous disease manifestations of histoplasmosis resolved with daily ketoconazole therapy. Disseminated histoplasmosis, with similar cutaneous features, also was present in his HIV-seropositive male sexual partner. The possibility of human-to-human transmission of histoplasmosis between these patients is considered and the skin lesions of systemic fungal infections in HIV-infected patients are reviewed.