Foundation for Research on Information Technologies in Society, Zeughausstr. 43, 8004 Zürich, Switzerland.
Phys Med Biol. 2010 Jan 21;55(2):N23-38. doi: 10.1088/0031-9155/55/2/N01. Epub 2009 Dec 17.
The objective of this study was to develop anatomically correct whole body human models of an adult male (34 years old), an adult female (26 years old) and two children (an 11-year-old girl and a six-year-old boy) for the optimized evaluation of electromagnetic exposure. These four models are referred to as the Virtual Family. They are based on high resolution magnetic resonance (MR) images of healthy volunteers. More than 80 different tissue types were distinguished during the segmentation. To improve the accuracy and the effectiveness of the segmentation, a novel semi-automated tool was used to analyze and segment the data. All tissues and organs were reconstructed as three-dimensional (3D) unstructured triangulated surface objects, yielding high precision images of individual features of the body. This greatly enhances the meshing flexibility and the accuracy with respect to thin tissue layers and small organs in comparison with the traditional voxel-based representation of anatomical models. Conformal computational techniques were also applied. The techniques and tools developed in this study can be used to more effectively develop future models and further improve the accuracy of the models for various applications. For research purposes, the four models are provided for free to the scientific community.
本研究的目的是开发用于优化电磁辐射评估的成人男性(34 岁)、成年女性(26 岁)和两个儿童(11 岁女孩和 6 岁男孩)的解剖学正确的整体人体模型。这四个模型被称为虚拟家庭。它们基于健康志愿者的高分辨率磁共振(MR)图像。在分割过程中区分了 80 多种不同的组织类型。为了提高分割的准确性和效率,使用了一种新的半自动工具来分析和分割数据。所有组织和器官都被重建为三维(3D)非结构化三角曲面物体,从而生成身体各个特征的高精度图像。与传统的基于体素的解剖模型表示相比,这极大地提高了针对薄组织层和小器官的网格灵活性和准确性。还应用了保形计算技术。本研究中开发的技术和工具可用于更有效地开发未来模型,并进一步提高各种应用模型的准确性。出于研究目的,这四个模型免费提供给科学界。