Department of Rheumatology, Hospital for Rheumatic Diseases, Hanyang University College of Medicine, 17 Haengdang-Dong, Sungdong-Gu, Seoul, 133-792, Republic of Korea.
Rheumatol Int. 2011 Mar;31(3):361-4. doi: 10.1007/s00296-009-1268-x. Epub 2009 Dec 18.
We investigated the prevalence and involvement patterns of radiographic osteoarthritis (OA) with hand symptoms among Korean people and compared the difference in prevalence of hand OA between racial groups. Hand radiographs in 299 Korean subjects (266 female, 33 male) ≥40 years of age were examined, who had hand arthralgia. The study population was comprised of 206 patients who had radiographic OA at least at one hand joint. Radiographic OA (Kellgren-Lawrence scale ≥2 grades) was evaluated for 16 joints of each hand. The most prevalent OA was in the interphalangeal joints (IP) of thumb, followed by the distal interphalangeal joints (DIP) of index finger, DIP of middle and fifth finger in the frequency of order. The involvement of metacarpophalangeal joints (MP) was relatively common in 1st-3rd MP. Hand OA in Korean was higher in the thumb IP and lower in the thumb carpometacarpal joints compared with Caucasian previously reported. Moreover, the higher OA frequency of 1st-3rd MP was not in accordance with other studies in Caucasian and other Asian populations. The patterns of radiographic hand OA were symmetric (OR 15.68), clustered by ray (OR 8.69) and row (OR 6.66). In conclusion, our study showed that thumb IP and 2nd/3rd/5th DIP should be included in the assessment of radiologic hand OA in Koreans.
我们调查了韩国人手部症状伴放射学骨关节炎（OA）的流行率和受累模式，并比较了不同种族人群手部 OA 的流行率差异。共检查了 299 名年龄≥40 岁、手部有疼痛性关节炎的韩国人（266 名女性，33 名男性）的手部 X 线片。研究人群包括 206 名至少有一个手部关节存在放射学 OA 的患者。对每只手的 16 个关节进行了放射学 OA（Kellgren-Lawrence 分级≥2 级）评估。最常见的 OA 发生在拇指指间关节（IP），其次是食指远侧指间关节（DIP），按频率顺序排列，中指和环指的 DIP 也较常见。第一至第三掌指关节（MP）的 MP 受累相对常见。与之前报道的高加索人相比，韩国人的手部 OA 在拇指 IP 更高，拇指掌指关节更低。此外，第一至第三 MP 的 OA 频率较高与高加索人和其他亚洲人群的其他研究不一致。手部放射学 OA 的模式为对称（OR 15.68），呈射线（OR 8.69）和行（OR 6.66）聚集。总之，我们的研究表明，拇指 IP 和第二/第三/第五远侧指间关节应纳入韩国人放射学手部 OA 的评估中。
