CRY Centre for Cardiac Pathology, National Heart and Lung Institute, Imperial College, London, UK.
Int J Legal Med. 2011 Jan;125(1):139-42. doi: 10.1007/s00414-009-0399-7. Epub 2009 Dec 18.
Cystic tumour of the atrioventricular nodal region is a rare primary cardiac tumour that can cause sudden death. Antemortem diagnosis and successful excision of this type of tumour are extremely rare. Three cases of sudden death are reported: A 25- and 40-year-old with a history of heart block and a 60-year-old with no medical history. There have been more than 120 cases of sudden death attributed to primary cardiac tumours in the literature. Although over 100 of these lesions were histologically benign, their intracardiac locations precipitated conductive and haemodynamic abnormalities that resulted in sudden death. The most common intracardiac lesion causing sudden death, cystic tumour of the atrioventricular node, however, may not be discovered unless the atrioventricular node is microscopically examined.
房室结区囊性肿瘤是一种罕见的原发性心脏肿瘤，可导致猝死。这种类型的肿瘤在生前诊断和成功切除极为罕见。报告了三例猝死病例：25 岁和 40 岁患者有心脏传导阻滞病史，60 岁患者无病史。文献中有 120 多例原发性心脏肿瘤导致的猝死病例。尽管其中超过 100 例病变在组织学上是良性的，但它们在心内的位置导致了传导和血液动力学异常，从而导致猝死。然而，最常见的导致猝死的心内病变，房室结区囊性肿瘤，如果不进行房室结的显微镜检查，可能无法发现。
