Cohle Stephen D
Spectrum Health, Grand Rapids, MI, USA.
Forensic Sci Res. 2019 May 16;4(3):287-289. doi: 10.1080/20961790.2019.1595349. eCollection 2019.
Cystic tumour of the atrioventricular node is the smallest tumour that can cause sudden cardiac death. This lesion arises from foregut endodermal rests which become enfolded into the heart during embryogenesis. Typically causing heart block, the tumour can cause sudden death despite pacemaker placement. Sudden death in such cases can be caused by arrhythmogenic ectopic foci arising from impaired electrical impulse propagation through the abnormal atrioventricular junction conducting tissue.
房室结囊性肿瘤是可导致心源性猝死的最小肿瘤。该病变起源于前肠内胚层残余组织,在胚胎发育过程中被卷入心脏。该肿瘤通常会导致心脏传导阻滞,即便植入起搏器仍可导致猝死。此类病例中的猝死可能由电冲动通过异常房室交界传导组织传播受损而产生的致心律失常异位灶引起。