Hu J Q, Guan Y H, Zhao L Z, Xie S X, Guo Z, Liang Z H
Department of Radiology, Guangdong Provincial Hospital, Guangzhou, People's Republic of China.
J Comput Assist Tomogr. 1991 Mar-Apr;15(2):181-7. doi: 10.1097/00004728-199103000-00001.
The CT features of 45 cases of delayed radiation encephalopathy (including radiation necrosis) following radiotherapy for nasopharyngeal carcinoma are reported. The brain lesions were uni- or bilateral and involved mainly the white matter and subsequently the gray matter of the lower portion of the brain included within the portals of irradiation and its vicinity. The lesions were edematous and hypodense on CT and showed postcontrast enhancement in 50% of the cases. Within the period of follow-up (1-5 years), the lesions showed remissions and exacerbations and in some cases stabilized. In addition, there was progressive cerebral atrophy, manifesting itself mainly as dilatation of the temporal horns, the neighboring cisterns, and sylvian fissures. In some cases that were followed for a long time, the cerebral lesions showed either foci of calcification or encephalomalacia and/or porencephaly.
报告了45例鼻咽癌放疗后迟发性放射性脑病（包括放射性坏死）的CT特征。脑病变为单侧或双侧，主要累及照射野及其附近脑下部的白质，随后累及灰质。病变在CT上呈水肿和低密度，50%的病例有增强表现。在随访期（1至5年）内，病变有缓解和加重，部分病例病变稳定。此外，有进行性脑萎缩，主要表现为颞角、相邻脑池和外侧裂增宽。在一些长期随访的病例中，脑病变显示有钙化灶或脑软化和/或脑穿通畸形。
