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迟发性脑放射性坏死的保守治疗

Conservative treatment of delayed cerebral radiation necrosis.

作者信息

Shaw P J, Bates D

出版信息

J Neurol Neurosurg Psychiatry. 1984 Dec;47(12):1338-41. doi: 10.1136/jnnp.47.12.1338.

DOI:10.1136/jnnp.47.12.1338
PMID:6512555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028144/
Abstract

A 63-year-old man developed delayed cerebral radiation necrosis following radiotherapy to a nasopharyngeal carcinoma. Complete resolution of his neurological deficit resulted from corticosteroid therapy alone. Serial CT scans showed the disappearance of the patients' mass lesion. The literature on cerebral necrosis following radiotherapy of extracranial neoplasms is reviewed with particular emphasis on management.

摘要

一名63岁男性在鼻咽癌放疗后发生迟发性脑放射性坏死。仅通过皮质类固醇治疗，其神经功能缺损就完全恢复。系列CT扫描显示患者的占位性病变消失。本文回顾了关于颅外肿瘤放疗后脑坏死的文献，特别强调了其治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7878/1028144/9b7b54f06a29/jnnpsyc00128-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7878/1028144/9b7b54f06a29/jnnpsyc00128-0077-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7878/1028144/9b7b54f06a29/jnnpsyc00128-0077-a.jpg

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1
Conservative treatment of delayed cerebral radiation necrosis.迟发性脑放射性坏死的保守治疗
J Neurol Neurosurg Psychiatry. 1984 Dec;47(12):1338-41. doi: 10.1136/jnnp.47.12.1338.
2
Delayed radiation encephalopathy after radiotherapy for nasopharyngeal cancer: a CT study of 45 cases.鼻咽癌放疗后迟发性放射性脑病：45例CT研究
J Comput Assist Tomogr. 1991 Mar-Apr;15(2):181-7. doi: 10.1097/00004728-199103000-00001.
3
Apoplectic intracerebral hemorrhage: an unusual complication of cerebral radiation necrosis.中风性脑出血：脑放射性坏死的一种罕见并发症。
Pathology. 1987 Jan;19(1):95-8. doi: 10.3109/00313028709065146.
4
Progressive white matter destruction following irradiation of an extracranial neoplasm.颅外肿瘤放疗后进行性白质破坏。
Ann Neurol. 1980 Jul;8(1):76-8. doi: 10.1002/ana.410080114.
5
[PET/CT-based classification of delayed radiation encephalopathy following radiotherapy for nasopharyngeal carcinoma].[基于PET/CT的鼻咽癌放疗后迟发性放射性脑病分类]
Nan Fang Yi Ke Da Xue Xue Bao. 2008 Mar;28(3):320-3.
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[Brain radionecrosis in patients irradiated for nasopharyngeal carcinoma: about nine cases].[鼻咽癌放疗患者的脑放射性坏死：附9例报告]
Cancer Radiother. 2007 Sep;11(5):234-40. doi: 10.1016/j.canrad.2007.04.001. Epub 2007 Jul 16.
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Radionecrosis of the brain presenting as a mass lesion: a case report.表现为肿块样病变的脑放射性坏死：病例报告
J Neurol Neurosurg Psychiatry. 1977 Aug;40(8):827-9. doi: 10.1136/jnnp.40.8.827.
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Cerebral radionecrosis in patients with nasopharyngeal carcinoma.鼻咽癌患者的脑放射性坏死
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Recurrent cystic radiation necrosis of the brain.
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Serial magnetic resonance imaging of delayed radiation necrosis treated with dexamethasone. Case illustration.地塞米松治疗迟发性放射性坏死的系列磁共振成像。病例说明。
J Neurosurg. 1997 Jun;86(6):1067. doi: 10.3171/jns.1997.86.6.1067.

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本文引用的文献

1
Amyloid degeneration of the human brain following X-ray therapy.X射线治疗后人脑的淀粉样变性
J Neuropathol Exp Neurol. 1950 Jan;9(1):93-102, illust. doi: 10.1097/00005072-195001000-00006.
2
LATE RADIATION NECROSIS OF THE BRAIN.
Wis Med J. 1964 Jul;63:297-300.
3
Necrosis of the brain following roentgen irradiation.X线照射后脑部坏死。
Am J Roentgenol Radium Ther Nucl Med. 1954 Dec;72(6):953-60.
A Multi-Disciplinary Approach to Diagnosis and Treatment of Radionecrosis in Malignant Gliomas and Cerebral Metastases.
一种针对恶性胶质瘤和脑转移瘤放射性坏死的多学科诊断与治疗方法。
Cancers (Basel). 2022 Dec 19;14(24):6264. doi: 10.3390/cancers14246264.
4
Bevacizumab Treatment of Radiation-Induced Brain Necrosis: A Systematic Review.贝伐单抗治疗放射性脑坏死：一项系统评价。
Front Oncol. 2021 Mar 25;11:593449. doi: 10.3389/fonc.2021.593449. eCollection 2021.
5
Temporal Lobe Necrosis Following Radiotherapy in Nasopharyngeal Carcinoma: New Insight Into the Management.鼻咽癌放疗后颞叶坏死：治疗新见解
Front Oncol. 2021 Jan 21;10:593487. doi: 10.3389/fonc.2020.593487. eCollection 2020.
6
Defining Treatment-Related Adverse Effects in Patients with Glioma: Distinctive Features of Pseudoprogression and Treatment-Induced Necrosis.定义胶质瘤患者的治疗相关不良反应：假性进展和治疗诱导性坏死的特征。
Oncologist. 2020 Aug;25(8):e1221-e1232. doi: 10.1634/theoncologist.2020-0085. Epub 2020 Jun 18.
7
Liquid Biopsy Strategies to Distinguish Progression from Pseudoprogression and Radiation Necrosis in Glioblastomas.液体活检策略区分胶质母细胞瘤的进展、假性进展和放射性坏死。
Adv Biosyst. 2020 Dec;4(12):e2000029. doi: 10.1002/adbi.202000029. Epub 2020 Jun 2.
8
A case report on intensive, robot-assisted rehabilitation program for brainstem radionecrosis.一例脑干放射性坏死的强化机器人辅助康复计划病例报告。
Medicine (Baltimore). 2020 Mar;99(10):e19517. doi: 10.1097/MD.0000000000019517.
9
Brain MR findings in patients treated with particle therapy for skull base tumors.接受粒子治疗的颅底肿瘤患者的脑部磁共振成像结果。
Insights Imaging. 2019 Sep 23;10(1):94. doi: 10.1186/s13244-019-0784-9.
10
Treatment-induced brain tissue necrosis: a clinical challenge in neuro-oncology.治疗诱导的脑组织坏死：神经肿瘤学的临床挑战。
Neuro Oncol. 2019 Sep 6;21(9):1118-1130. doi: 10.1093/neuonc/noz048.
4
Brain necrosis following X-ray therapy.X射线治疗后发生的脑坏死。
J Neurosurg. 1953 Jul;10(4):423-9. doi: 10.3171/jns.1953.10.4.0423.
5
Therapeutic irradiation and brain injury.治疗性照射与脑损伤。
Int J Radiat Oncol Biol Phys. 1980 Sep;6(9):1215-28. doi: 10.1016/0360-3016(80)90175-3.
6
Delayed brain necrosis in irradiated adenoid cystic carcinoma nose--a case report.放疗后腺样囊性癌鼻腔延迟性脑坏死——病例报告
Indian J Cancer. 1980 Mar;17(1):59-63.
7
[Delayed cerebral radionecrosis with pseudo-tumoral evolution].[具有假瘤样演变的迟发性脑放射性坏死]
Minerva Neurochir. 1967;11(1):28-41.
8
The nature of latent cerebral irradiation damage and its modification by hypertension.潜在性脑辐射损伤的本质及其与高血压的关系。
Br J Radiol. 1970 Mar;43(507):161-7. doi: 10.1259/0007-1285-43-507-161.
9
[Late cerebral radionecrosis with hypertensive endocranial evolution].[伴有高血压性颅内进展的迟发性脑放射性坏死]
G Psichiatr Neuropatol. 1967;95(3):533-45.
10
Radiation encephalopathy--an autopsy case and some comments on the pathogenesis of delayed radionecrosis of central nervous system.放射性脑病——1例尸检病例及对中枢神经系统迟发性放射性坏死发病机制的若干评论
Acta Pathol Jpn. 1973 Nov;23(4):867-83. doi: 10.1111/j.1440-1827.1973.tb02781.x.