Schaefer G B, Thompson J N, Bodensteiner J B, Gingold M, Wilson M, Wilson D
Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City.
J Child Neurol. 1991 Jan;6(1):15-9. doi: 10.1177/088307389100600103.
We have established a normative data set for the relative size of the structures of the midline posterior fossa from birth to 90 years old. Data were obtained from morphometric analysis of midsagittal magnetic resonance imaging scans of the brain utilizing a simple image analysis system. There are several significant changes in the size of these structures with an increase in chronologic age. The relative size of the cisterna magna decreases with age. Anterior cerebellar vermal lobules (I through V) appear to grow more rapidly than the rest of the cerebellum. Other, less significant, trends include a decrease in the overall size of the cerebellum, superior posterior vermal lobules (VI and VII) and inferior posterior lobule (VIII) with an increase in age. It is, therefore, necessary to use age-standardized normative data when making morphometric correlations with clinical disorders.
我们已经建立了一个从出生到90岁的后颅窝中线结构相对大小的标准数据集。数据来自于利用一个简单图像分析系统对大脑矢状位磁共振成像扫描进行的形态测量分析。随着实际年龄的增加，这些结构的大小有几个显著变化。枕大池的相对大小随年龄减小。小脑蚓部前叶（I至V）似乎比小脑的其他部分生长得更快。其他不太显著的趋势包括随着年龄增加，小脑、小脑蚓部后上叶（VI和VII）和后下叶（VIII）的整体大小减小。因此，在将形态测量与临床疾病进行关联时，有必要使用年龄标准化的标准数据。
