Lhuissier M, Suschetet M, Causeret J
Ann Nutr Aliment. 1976;30(5-6):847-58.
Nitrites--and sometimes nitrates--decrease the biological availability of dietary vitamins in several animal species. 1. Numerous studies show that ingested nitrites decrease the stock of liver vitamin A in nonruminants (Rat, Pig, Chicken); the effect of nitrates is less pronounced even lacking. In vitro, experiments allow to think that vitamin A and beta-carotene can be destroyed by nitrites in the diet and/or in the gastrointestinal tract. 2. Some recent works--those of Lhuissier particularly--show that nitrites can affect some vitamins of B group and their metabolism. Thiamine and vitamin B6 contents of several tissues decrease when nitrites are fed to the Rat. In the case of thiamine, the result could be partially explained by destruction of the vitamin in the diet and may be in the gastrointestinal tract. No such explanation seems to be possible in the case of vitamin B6.
亚硝酸盐（有时还有硝酸盐）会降低多种动物膳食维生素的生物利用率。1. 大量研究表明，摄入的亚硝酸盐会减少非反刍动物（大鼠、猪、鸡）肝脏中维生素A的储备；硝酸盐的影响则不那么明显，甚至没有影响。在体外实验中，可以认为维生素A和β-胡萝卜素会在饮食和/或胃肠道中被亚硝酸盐破坏。2. 一些近期的研究——尤其是吕西耶的研究——表明，亚硝酸盐会影响某些B族维生素及其代谢。给大鼠喂食亚硝酸盐后，几种组织中的硫胺素和维生素B6含量会降低。就硫胺素而言，这一结果部分可以通过饮食中维生素的破坏以及可能在胃肠道中的破坏来解释。而对于维生素B6，似乎无法给出这样的解释。
