Leclerc J
Ann Nutr Aliment. 1978;32(4):753-63.
Nine and twenty-one months old rats fed a balanced diet were given for 5 weeks an extra supplementation in thiamine, riboflavin and vitamin B6. Control animals were given the same diet but without vitamin extra supplementation. Fecal and urinary vitamin excretions were determined during this 5 weeks period. They were shown to be less important in older rats than in younger ones. Influence of aging and vitamin supplementation on the vitamin contents of organs and tissues were studied on these animals: previous results were confirmed [see LECLERC, Ann. nutrit, Aliment., 1976, 30, 10--25]. From these results and others published elsewhere, it is conclused that in older animals there could be an increased intestinal destruction of the above mentionned vitamin although changes in vitamin metabolism can be involved too.
给9个月和21个月大、食用均衡饮食的大鼠额外补充硫胺素、核黄素和维生素B6，持续5周。对照动物食用相同饮食，但不额外补充维生素。在这5周期间测定粪便和尿液中的维生素排泄量。结果表明，这些排泄量在老年大鼠中比在年轻大鼠中要少。研究了衰老和维生素补充对这些动物器官和组织中维生素含量的影响：先前的结果得到了证实[见勒克莱尔，《营养与食品》，1976年，30卷，第10 - 25页]。从这些结果以及其他地方发表的结果可以得出结论，在老年动物中，上述维生素的肠道破坏可能会增加，不过维生素代谢的变化也可能起作用。
