MacDonald Shannon M, Yock Torunn I
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Cox 340, 100 Blossom Street, Boston, MA 02114, USA.
Childs Nerv Syst. 2010 Mar;26(3):285-91. doi: 10.1007/s00381-009-1059-4. Epub 2009 Dec 19.
Proton radiation therapy is a form of radiation with physical properties that can provide an advantage in normal tissue sparing compared to the more commonly used photon therapy.
The greatest benefit may be for young patients with tumors requiring relatively high doses of radiation and adjacent to critical structures. Children with central nervous system ependymomas meet these criteria and have a very high likelihood of benefit from proton radiation. At present, proton radiation is limited to select centers. However, knowledge of many of the physical advantages of proton therapy has spread rapidly over the past several years, and its availability is becoming more widespread.
质子放射治疗是一种放射形式,与更常用的光子治疗相比,其物理特性在保护正常组织方面具有优势。
最大的益处可能在于患有需要相对高剂量放射且肿瘤邻近关键结构的年轻患者。患有中枢神经系统室管膜瘤的儿童符合这些标准,并且极有可能从质子放射治疗中获益。目前,质子放射治疗仅限于特定的中心。然而,在过去几年中,关于质子治疗诸多物理优势的知识传播迅速,其可及性也越来越广泛。