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多发性硬化症患者调整组的评估:一项试点随机对照试验。

Evaluation of an adjustment group for people with multiple sclerosis: a pilot randomized controlled trial.

机构信息

Institute of Work, Health and Organisations, University of Nottingham, Nottingham, UK.

出版信息

Clin Rehabil. 2010 Mar;24(3):211-21. doi: 10.1177/0269215509343492. Epub 2009 Dec 21.

DOI:10.1177/0269215509343492
PMID:20026575
Abstract

OBJECTIVE

The aim was to evaluate a group treatment for people with multiple sclerosis and low mood.

DESIGN

Randomized controlled trial.

SETTING

Community.

PARTICIPANTS

Patients with multiple sclerosis and low mood, scoring >7 on the Hospital Anxiety and Depression Scales or >2 on the General Health Questionnaire 12.

INTERVENTIONS

Participants either attended an adjustment group for six, 2-hour group treatment sessions or were on a waiting list to attend the group.

OUTCOMES

Hospital Anxiety and Depression Scale, General Health Questionnaire 12, Multiple Sclerosis Self Efficacy Scale, Multiple Sclerosis Impact Scale and Short Form 36 administered 3 and 6 months after random allocation.

RESULTS

Of the 219 patients identified, 100 (46%) reported depressive symptoms and 126 (58%) anxiety symptoms. Forty participants were recruited, aged 25-68 (mean 47.7 SD 9.7) and eight were men. Patients allocated to the group intervention reported fewer depressive symptoms than those in the control group (U 109.5, P<0.05) but there were no significant differences in anxiety symptoms, self-efficacy or quality of life.

CONCLUSION

Depressive symptoms were reduced following group intervention, which suggests this may be an effective psychological treatment and warrants further evaluation.

摘要

目的

评估一种针对多发性硬化症伴情绪低落患者的团体治疗方法。

设计

随机对照试验。

地点

社区。

参与者

多发性硬化症伴情绪低落、医院焦虑抑郁量表评分>7 或一般健康问卷 12 评分>2 的患者。

干预措施

参与者参加为期 6 次、每次 2 小时的调整团体治疗组或在等待名单上等待参加团体治疗。

结果

在确定的 219 名患者中,有 100 名(46%)报告有抑郁症状,126 名(58%)有焦虑症状。招募了 40 名参与者,年龄 25-68 岁(平均 47.7±9.7),其中 8 名为男性。与对照组相比,接受团体干预的患者报告的抑郁症状较少(U=109.5,P<0.05),但焦虑症状、自我效能感或生活质量无显著差异。

结论

团体干预后抑郁症状有所减轻,这表明这可能是一种有效的心理治疗方法,值得进一步评估。

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