糖尿病患者的死亡率与收入相关的差异。

Income-related differences in mortality among people with diabetes mellitus.

机构信息

Institute for Clinical Evaluative Sciences, Toronto, Ont.

出版信息

CMAJ. 2010 Jan 12;182(1):E1-E17. doi: 10.1503/cmaj.090495. Epub 2009 Dec 21.

Abstract

BACKGROUND

Mortality has declined substantially among people with diabetes mellitus over the last decade. Whether all income groups have benefited equally, however, is unclear. We examined the impact of income on mortality trends among people with diabetes.

METHODS

In this population-based, retrospective cohort study, we compared changes in mortality from Apr. 1, 1994, to Mar. 31, 2005, by neighbourhood income strata among people with diabetes aged 30 years or more in the province of Ontario, Canada.

RESULTS

Overall, the annual age- and sex-adjusted mortality declined, from 4.05% in 1994/95 (95% confidence interval [CI] 3.98%-4.11%) to 2.69% in 2005/06 (95% CI 2.66%-2.73%). The decrease was significantly greater in the highest income group (by 36%) than in the lowest income group (by 31%; p < 0.001). This trend was most pronounced in the younger group (age 30-64 years): the mortality rate ratio widened by more than 40% between the lowest and highest income groups, from 1.12 to 1.59 among women and from 1.14 to 1.60 among men. Income had a much smaller effect on mortality trends in the older group, whose drug costs are subsidized: the income-related difference rose by only 0.9% over the study period.

INTERPRETATION

Mortality declined overall among people with diabetes from 1994 to 2005; however, the decrease was substantially greater in the highest income group than in the lowest, particularly among those aged 30-64 years. These findings illustrate the increasing impact of income on the health of people with diabetes even in a publicly funded health care setting. Further studies are needed to explore factors responsible for these income-related differences in mortality.

摘要

背景

在过去的十年中,糖尿病患者的死亡率大幅下降。然而,尚不清楚所有收入群体是否都同等受益。我们研究了收入对糖尿病患者死亡率趋势的影响。

方法

在这项基于人群的回顾性队列研究中,我们比较了加拿大安大略省年龄在 30 岁及以上的糖尿病患者,在不同社区收入阶层中,1994 年 4 月 1 日至 2005 年 3 月 31 日期间,死亡率的变化。

结果

总体而言,经过年龄和性别调整后的年死亡率从 1994/95 年的 4.05%(95%置信区间[CI]为 3.98%-4.11%)下降到 2005/06 年的 2.69%(95%CI 为 2.66%-2.73%)。最高收入组的降幅(36%)明显大于最低收入组(31%;p<0.001)。这一趋势在较年轻的组(30-64 岁)中最为明显:在最低和最高收入组之间,死亡率比率扩大了 40%以上,女性从 1.12 增加到 1.59,男性从 1.14 增加到 1.60。在年龄较大的组中,药物费用得到补贴,因此收入对死亡率趋势的影响要小得多:在研究期间,收入相关差异仅上升了 0.9%。

结论

1994 年至 2005 年期间,糖尿病患者的总体死亡率下降;然而,最高收入组的降幅明显大于最低收入组,尤其是在 30-64 岁的人群中。这些发现表明,即使在公共资助的医疗保健环境中,收入对糖尿病患者健康的影响也在不断增加。需要进一步研究来探讨导致这些与收入相关的死亡率差异的因素。

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