Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
Diabetes Res Clin Pract. 2013 Mar;99(3):372-9. doi: 10.1016/j.diabres.2012.12.005. Epub 2013 Jan 8.
Diabetes rates are increasing dramatically, and certain populations are at greater risk. Low income status is associated with higher diabetes prevalence and higher mortality. The effect of income on diabetes incidence is less well understood.
Using a validated, population-based diabetes registry and census data from Ontario, Canada, we compared the rate of new diabetes cases among persons aged 20 years or older between April 1st 2006 and March 31st 2007 between neighborhood income quintiles, and assessed for age- and sex-based differences.
There were 88,886 new cases of diabetes in Ontario adults during our study period (incidence rate 8.26/1000, 95% confidence interval, CI 8.20-8.31). Rates increased with age and were higher in males versus females. Increasing income quintile was associated with a significantly decreased diabetes incidence (8.70/1000, 95% CI 8.57-8.82 in the lowest quintile, vs. 7.25/1000, 95% CI 7.14-7.36 in the highest quintile, p<0.0001). Significant interactions were found between income quintile (1, 2, and 3 vs. 5) and age groups (20-39, 40-59 vs. 80+ years) (p<0.01) and sex (p<0.01), such that the impact of income was more pronounced in younger compared to older age groups and in females versus males.
This population-based study found that diabetes risk is significantly higher in lower compared to higher income groups, and that this income gap was widest in younger persons and females. Greater diabetes preventive efforts directed toward younger and female lower-income populations are necessary, in order to lessen the lifelong burden of diabetes for an already disadvantaged population.
糖尿病发病率正在急剧上升,某些人群的风险更高。低收入与更高的糖尿病患病率和更高的死亡率相关。收入对糖尿病发病率的影响则不太清楚。
我们使用经过验证的基于人群的糖尿病登记处和来自加拿大安大略省的人口普查数据,比较了 2006 年 4 月 1 日至 2007 年 3 月 31 日期间,20 岁或以上人群中每 1000 人中新发糖尿病病例在社区收入五分位数之间的差异,并评估了年龄和性别差异。
在我们的研究期间,安大略省成年人中有 88886 例新发糖尿病(发病率为 8.26/1000,95%置信区间,CI 8.20-8.31)。发病率随年龄增长而增加,且男性高于女性。收入五分位数的增加与糖尿病发病率的显著下降相关(五分位数最低的为 8.70/1000,95%CI 8.57-8.82,五分位数最高的为 7.25/1000,95%CI 7.14-7.36,p<0.0001)。收入五分位数(1、2 和 3 与 5)与年龄组(20-39、40-59 与 80+岁)之间(p<0.01)和性别(p<0.01)之间存在显著的交互作用,表明与较年长的年龄组相比,收入的影响在较年轻的年龄组中更为明显,在女性中比男性更为明显。
这项基于人群的研究发现,与高收入组相比,低收入组的糖尿病风险明显更高,而在年轻人群和女性中,这种收入差距最大。为了减轻已经处于不利地位的人群终生患糖尿病的负担,需要针对年轻和低收入的女性群体加大糖尿病预防力度。