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腹腔镜手术治疗复发性回肠末端克罗恩病。

Laparoscopic surgery for recurrent ileocolic Crohn's disease.

机构信息

Division of Colon and Rectal Surgery, Mayo Clinic Rochester, Minnesota, USA.

出版信息

Inflamm Bowel Dis. 2010 Aug;16(8):1382-6. doi: 10.1002/ibd.21186.

Abstract

BACKGROUND

Laparoscopic (LAP) surgery is increasingly performed for primary ileocolic Crohn's disease (CD), but its application in patients with recurrent ileocolic CD is less well described. Our aim was to assess whether or not a laparoscopic approach was safe, feasible, and conferred meaningful short-term benefits in this patient population.

METHODS

Patients undergoing LAP surgery for recurrent ileocolic CD at our institution from 1998-2008 were identified using a prospectively maintained database. Potential risk factors for conversion to open surgery and overall patient outcomes were assessed with univariate analysis.

RESULTS

Forty patients were identified, of which 30 (75%) were LAP-completed and 10 (25%) were LAP-converted. The groups did not differ with respect to clinicopathological features. LAP-converted patients were significantly more likely to require adhesiolysis than LAP-completed patients (100% versus 67%, P = 0.04). There was 1 intraoperative complication in a converted patient. LAP-converted patients had longer times to soft diet (4 versus 3 days, P = 0.03) and longer length of stay (7 versus 4 days, P = 0.003). The groups did not differ with respect to incidence of postoperative complications or frequency of readmission within 30 days. There was no mortality.

CONCLUSIONS

In up to 20% of patients with recurrent ileocolic, successful laparoscopic re-resection may be prevented by adhesions. Conversion increased the length of stay without increasing morbidity. We conclude that LAP surgery can be safely performed in selected patients with recurrent ileocolic CD and leads to short-term benefits.

摘要

背景

腹腔镜(LAP)手术越来越多地用于原发性回结肠克罗恩病(CD),但其在复发性回结肠 CD 患者中的应用描述较少。我们的目的是评估在这种患者人群中,腹腔镜方法是否安全、可行,并具有有意义的短期益处。

方法

使用前瞻性维护的数据库,确定了 1998-2008 年在我院接受腹腔镜手术治疗复发性回结肠 CD 的患者。使用单变量分析评估了转换为开放性手术的潜在风险因素和总体患者结局。

结果

确定了 40 例患者,其中 30 例(75%)完成了 LAP 手术,10 例(25%)转换为 LAP 手术。两组在临床病理特征方面无差异。与 LAP 完成组相比,LAP 转换组患者更有可能需要粘连松解(100%对 67%,P = 0.04)。在转换患者中有 1 例术中并发症。LAP 转换患者恢复软食的时间更长(4 天对 3 天,P = 0.03),住院时间更长(7 天对 4 天,P = 0.003)。两组术后并发症发生率或 30 天内再入院频率无差异。无死亡。

结论

在多达 20%的复发性回结肠患者中,粘连可能会阻止成功的腹腔镜再切除。转换增加了住院时间,而没有增加发病率。我们得出结论,LAP 手术可安全地用于选定的复发性回结肠 CD 患者,并带来短期益处。

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