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移植肾后曲霉菌感染致髂动脉假性动脉瘤。

Pseudoaneurysm of the iliac artery secondary to Aspergillus infection after kidney transplantation.

机构信息

Department of Surgery, Tao Yuan Armed Forces General Hospital, Taoyuan, Taiwan, R.O.C.

出版信息

J Chin Med Assoc. 2009 Dec;72(12):654-6. doi: 10.1016/S1726-4901(09)70450-2.

Abstract

Infectious complications are the top causes of morbidity and mortality in patients who undergo renal transplantation. We report a patient who received a cadaveric renal transplant in Mainland China. One year post-transplantation, the patient had right buttock pain with radiation to the leg. Swelling and tenderness over the right groin was also found. Magnetic resonance imaging revealed a multilobulated cystic lesion, about 8 x 7 cm, at the right iliac fossa and presacral region extending to the posterior aspect of the graft kidney and up to the right psoas muscle. Drainage of the intra-abdominal abscess was performed. The abscess culture showed presence of Aspergillus spp. The patient had received steroids, tacrolimus and mycophenolate mofetil, which could be a risk factor for fungal infection. The cause of Aspergillus infection in our patient remains unclear. It may have been due to immune system insufficiency of the patient rendering the patient prone to infection. Pseudoaneurysm formation of the internal iliac artery following Aspergillus infection after kidney transplantation is rarely reported. Although it is a dilemma, once a severe situation such as pseudoaneurysm with aspergillosis presents, graft removal is suggested.

摘要

感染并发症是肾移植患者发病率和死亡率的主要原因。我们报告了 1 例在中国内地接受尸体肾移植的患者。移植后 1 年,患者出现右侧臀部疼痛,放射至腿部。还发现右侧腹股沟肿胀和压痛。磁共振成像显示右侧髂窝和骨盆腔前区有一个多叶囊性病变,约 8 x 7 厘米,延伸至移植肾的后外侧和右侧腰大肌。进行了腹腔脓肿引流。脓肿培养显示存在曲霉菌属。患者曾接受类固醇、他克莫司和霉酚酸酯治疗,这可能是真菌感染的危险因素。我们患者的曲霉菌感染的原因尚不清楚。可能是由于患者的免疫系统功能不足,使患者容易感染。肾移植后曲霉菌感染导致的髂内动脉假性动脉瘤形成很少见。虽然这是一个困境,但一旦出现严重的情况,如伴有曲霉菌感染的假性动脉瘤,建议进行移植物切除。

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