比较临床和实验室标准协会肉汤微量稀释法（M27-A3 文件）和 Etest 测定念珠菌属分离株的阿尼芬净 MIC 值。
Comparison of anidulafungin MICs determined by the clinical and laboratory standards institute broth microdilution method (M27-A3 document) and Etest for Candida species isolates.
机构信息
VCU Medical Center, Richmond, Virginia, USA.
出版信息
Antimicrob Agents Chemother. 2010 Mar;54(3):1347-50. doi: 10.1128/AAC.01324-09. Epub 2009 Dec 22.
Abstract
Anidulafungin Etest and CLSI MICs were compared for 143 Candida sp. isolates to assess essential (within 2 log(2) dilutions) and categorical agreements (according to three susceptibility breakpoints). Based on agreement percentages, our data indicated that Etest is not suitable to test anidulafungin against Candida parapsilosis and C. guilliermondii (54.4 to 82.4% essential and categorical agreements) but is more suitable for C. albicans, C. glabrata, C. krusei, and C. tropicalis (87.9 to 100% categorical agreement).
摘要
对 143 株念珠菌属分离株进行了棘白菌素 E 试验和 CLSI MIC 的比较，以评估基本（在 2 个对数稀释度内）和分类一致性（根据三个药敏折点）。根据一致性百分比，我们的数据表明棘白菌素 E 试验不适用于检测近平滑念珠菌和热带念珠菌对棘白菌素的敏感性（基本和分类一致性为 54.4%至 82.4%），但更适用于白色念珠菌、光滑念珠菌、克柔念珠菌和热带念珠菌（分类一致性为 87.9%至 100%）。
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