Department of Respiratory Medicine, Chorley and South Ribble Hospital, Lancashire Teaching Hospitals NHS Foundation Trust, Preston Road, Chorley PR7 1PP, UK.
Thorax. 2010 Jan;65(1):82-4. doi: 10.1136/thx.2009.121418.
Diffuse interlobular septal thickening (DIST) is an abnormality seen on high-resolution CT (HRCT) scanning of the thorax. While DIST may be present to variable extents in a number of lung conditions, it is uncommon as a predominant finding except in a few entities. This report features an ex-coal miner, thought to have coal workers' pneumoconiosis (CWP), in whom the HRCT scan showed no evidence of CWP and instead showed DIST. The patient's condition progressed incessantly towards death from severe secondary pulmonary hypertension. The case links fatal pulmonary hypertension to DIST, a pattern not previously described in coal workers.
弥漫性小叶间隔增厚(DIST)是胸部高分辨率 CT(HRCT)扫描的异常表现。虽然 DIST 在许多肺部疾病中都有不同程度的存在,但除了少数几种情况外,它并不常见作为主要发现。本报告介绍了一名前煤矿工人,据认为患有煤工尘肺(CWP),其 HRCT 扫描没有显示 CWP 的证据,而是显示了 DIST。患者的病情不断恶化,最终死于严重的继发性肺动脉高压。该病例将致命性肺动脉高压与之前在煤矿工人中未描述过的 DIST 模式联系起来。