Division of Neurosurgery, Dalhousie University, Halifax, Nova Scotia, Canada.
J Neurotrauma. 2011 Aug;28(8):1479-95. doi: 10.1089/neu.2009.1156. Epub 2010 Apr 8.
Intensive cardiopulmonary management is frequently undertaken in patients with spinal cord injury (SCI), particularly due to the occurrence of neurogenic shock and ventilatory insufficiency and in an attempt to reduce secondary injury. We undertook a systematic review of the literature to examine the evidence that intensive care management improves outcome after SCI and to attempt to define key parameters for cardiopulmonary support/resuscitation. We review the literature in five areas: management of SCI patients in specialized centers, risk in SCI patients of cardiopulmonary complications, parameters for blood pressure and oxygenation/ventilation support following SCI, risk factors for cardiopulmonary insufficiency requiring ICU care after SCI, and preventative strategies to reduce the risks of cardiopulmonary complications in SCI patients. The literature supports that, in light of the significant incidence of cardiorespiratory complications, SCI patients should be managed in a monitored special care unit. There is weak evidence supporting the maintenance of MAP >85 mmHg for a period extending up to 1 week following SCI.
脊髓损伤(SCI)患者常需要进行强化心肺管理,特别是由于发生神经源性休克和通气不足,并试图减少继发性损伤。我们对文献进行了系统回顾,以检查强化监护管理是否能改善 SCI 后的预后,并尝试确定心肺支持/复苏的关键参数。我们从五个方面回顾了文献:专门中心的 SCI 患者管理、SCI 患者发生心肺并发症的风险、SCI 后血压和氧合/通气支持的参数、需要 ICU 治疗的 SCI 后心肺功能不全的危险因素,以及降低 SCI 患者心肺并发症风险的预防策略。文献表明,鉴于心肺并发症的高发生率,SCI 患者应在监护特殊护理单元中进行管理。有微弱的证据支持在 SCI 后长达 1 周的时间内维持 MAP >85mmHg。