Prevention Science Collaborative, San Diego State University, San Diego, CA 92120, United States.
Drug Alcohol Depend. 2010 Apr 1;108(1-2):138-40. doi: 10.1016/j.drugalcdep.2009.11.010. Epub 2009 Dec 23.
Salvia divinorum (salvia) is an intense, short-acting hallucinogenic plant gaining popularity among adolescents in the United States. There has been little scientific documentation of salvia's effects. The popular video-sharing website YouTube has received literally thousands of video-posts of people using salvia. The objective of this study was to assess the effects of salvia use through systematic observations of YouTube videos. A sample of salvia videos was obtained using the search term "salvia." The videos were further screened and only videos that captured the entire drug "trip" without video edits were included in the analyses described here (n=34). Three trained research assistants independently watched the videos and rated their observations on 42 effects in 30-s intervals. Onset of symptoms was quick (often less than 30s) and tended to dissipate within 8min. Further, there was a relationship between salvia dose and effect duration. Since salvia's effects on humans are largely undocumented, this study provides the look at users in a non-laboratory environment (e.g. self-taped videos) exhibiting impairments and behaviors consistent with this powerful hallucinogen. Also, this study demonstrates the feasibility and shortcomings of using YouTube videos to assess emerging drugs and drug effects.
迷幻鼠尾草（迷幻鼠尾草）是一种强烈的、短时间作用的致幻植物，在美国青少年中越来越受欢迎。关于迷幻鼠尾草的影响，科学文献记载很少。流行的视频分享网站 YouTube 上已经收到了成千上万的人使用迷幻鼠尾草的视频帖子。这项研究的目的是通过对 YouTube 视频的系统观察来评估迷幻鼠尾草的使用效果。使用搜索词“迷幻鼠尾草”获得了迷幻鼠尾草视频样本。对视频进行了进一步筛选，只有那些没有视频编辑的完整药物“旅行”的视频才被包括在本文描述的分析中（n=34）。三名经过培训的研究助理独立观看视频，并在 30 秒的间隔内对他们的观察结果进行了 42 种效果的评分。症状的发作很快（通常不到 30 秒），并倾向于在 8 分钟内消散。此外，迷幻鼠尾草的剂量和作用持续时间之间存在关系。由于人类对迷幻鼠尾草的影响在很大程度上没有记录，因此这项研究提供了在非实验室环境（例如，自我录制的视频）中观察到的使用者的情况，他们表现出与这种强效致幻剂一致的损伤和行为。此外，这项研究还展示了使用 YouTube 视频来评估新兴药物和药物效果的可行性和局限性。
