Determination of paraoxonase 1 status without the use of toxic organophosphate substrates.
作者信息
Richter Rebecca J, Jarvik Gail P, Furlong Clement E
机构信息
Department, of Medicine-Division of Medical Genetics and Genome Sciences, University of Washington, Seattle, WA 98195-7720, USA.
出版信息
Circ Cardiovasc Genet. 2008 Dec;1(2):147-52. doi: 10.1161/CIRCGENETICS.108.811638.
Abstract
摘要
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Determination of paraoxonase 1 status and genotypes at specific polymorphic sites.对特定多态性位点的对氧磷酶1状态和基因型的测定。
Curr Protoc Toxicol. 2004 May;Chapter 4:Unit4.12. doi: 10.1002/0471140856.tx0412s19.
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Genetic and environmental determinants of the PON-1 phenotype.对氧磷酶-1（PON-1）表型的遗传和环境决定因素。
Eur J Clin Invest. 2007 Mar;37(3):187-96. doi: 10.1111/j.1365-2362.2007.01769.x.
3
A long and winding road: defining the biological role and clinical importance of paraoxonases.一条漫长而曲折的道路：界定对氧磷酶的生物学作用和临床重要性
Clin Chem Lab Med. 2006;44(9):1052-9. doi: 10.1515/CCLM.2006.207.
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The association of the PON1 Q192R polymorphism with complications and outcomes of pregnancy: findings from the British Women's Heart and Health cohort study.对氧磷酶1（PON1）Q192R基因多态性与妊娠并发症及结局的关联：来自英国女性心脏与健康队列研究的结果
Paediatr Perinat Epidemiol. 2006 May;20(3):244-50. doi: 10.1111/j.1365-3016.2006.00716.x.
5
PON1 status of farmworker mothers and children as a predictor of organophosphate sensitivity.农场工人母亲和儿童的对氧磷酶1状态作为有机磷敏感性的预测指标。
Pharmacogenet Genomics. 2006 Mar;16(3):183-90. doi: 10.1097/01.fpc.0000189796.21770.d3.
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Toxicity of chlorpyrifos and chlorpyrifos oxon in a transgenic mouse model of the human paraoxonase (PON1) Q192R polymorphism.毒死蜱和对氧磷在人类对氧磷酶（PON1）Q192R多态性转基因小鼠模型中的毒性。
Pharmacogenet Genomics. 2005 Aug;15(8):589-98. doi: 10.1097/01.fpc.0000167327.08034.d2.
7
Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?对氧磷酶1与动脉粥样硬化：基因还是蛋白质更重要？
Free Radic Biol Med. 2004 Nov 1;37(9):1317-23. doi: 10.1016/j.freeradbiomed.2004.07.034.
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Genetic and environmental factors modulating serum concentrations and activities of the antioxidant enzyme paraoxonase-1.调节抗氧化酶对氧磷酶-1血清浓度及活性的遗传和环境因素。
Clin Sci (Lond). 2004 Nov;107(5):435-47. doi: 10.1042/CS20040187.
9
Four paraoxonase gene polymorphisms in 11212 cases of coronary heart disease and 12786 controls: meta-analysis of 43 studies.11212例冠心病患者和12786例对照中的四种对氧磷酶基因多态性：43项研究的荟萃分析
Lancet. 2004 Feb 28;363(9410):689-95. doi: 10.1016/S0140-6736(04)15642-0.
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Pharmacogenetics of paraoxonases: a brief review.对氧磷酶的药物遗传学：简要综述。
Naunyn Schmiedebergs Arch Pharmacol. 2004 Jan;369(1):78-88. doi: 10.1007/s00210-003-0833-1. Epub 2003 Oct 25.
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