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结肠镜检查中用于区分结肠增生性息肉和腺瘤性息肉的光学活检系统。

Optical biopsy system distinguishing between hyperplastic and adenomatous polyps in the colon during colonoscopy.

机构信息

Thomayer Teaching Hospital, Videnska 800, 140 00 Prague 4, Czech Republic.

出版信息

Anticancer Res. 2009 Nov;29(11):4737-9.

PMID:20032428
Abstract

BACKGROUND

It has been established that the removal of adenomatous colon polyps drastically reduces the incidence of colorectal cancer (CRC), but polypectomy is not without risk. The aim was to determine the correlation between the results of an optical biopsy system and the histopathology report of the physical biopsy specimens of the same polyps removed at colonoscopy.

PATIENTS AND METHODS

Paired optical and physical biopsies were performed on 55 polyps with complete polypectomy of the same tissue.

RESULTS

Fifty-three adenomatous polyps and two hyperplastic polyps were identified by the hospital pathologist. The optical biopsy system identified 52 polyps as suspect (adenomatous) and 2 as non-suspect (hyperplastic). One villous adenoma could not be optically analyzed due to friability.

CONCLUSION

The WavSTAT Optical Biopsy System provides accurate information to the gastroenterologist to assist in distinguishing between hyperplastic and adenomatous polyps. It is safe for the patient and does not unduly increase the time required for an endoscopic examination.

摘要

背景

已经证实,切除腺瘤性结肠息肉可显著降低结直肠癌(CRC)的发病率,但息肉切除术并非没有风险。目的是确定光学活检系统的结果与结肠镜切除的相同息肉的物理活检标本的组织病理学报告之间的相关性。

患者和方法

对 55 个完全切除息肉的息肉进行了光学和物理活检的配对。

结果

医院病理学家鉴定出 53 个腺瘤性息肉和 2 个增生性息肉。光学活检系统鉴定出 52 个息肉为可疑(腺瘤性),2 个为非可疑(增生性)。由于易碎性,一个绒毛状腺瘤无法进行光学分析。

结论

WavSTAT 光学活检系统为胃肠病学家提供了准确的信息,以帮助区分增生性和腺瘤性息肉。它对患者是安全的,并且不会不必要地增加内镜检查所需的时间。

相似文献

1
Optical biopsy system distinguishing between hyperplastic and adenomatous polyps in the colon during colonoscopy.结肠镜检查中用于区分结肠增生性息肉和腺瘤性息肉的光学活检系统。
Anticancer Res. 2009 Nov;29(11):4737-9.
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Step section histology of proximal colon polyps that appear hyperplastic by endoscopy.经内镜检查显示为增生性的近端结肠息肉的阶梯切片组织学检查。
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Evaluation of autofluorescence colonoscopy for the detection and diagnosis of colonic polyps.自体荧光结肠镜用于检测和诊断结肠息肉的评估。
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Increased incidence of colorectal adenomas in follow-up evaluation of patients with newly diagnosed hyperplastic polyps.新诊断增生性息肉患者随访评估中结直肠腺瘤发病率增加。
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Chromocolonoscopy detects more adenomas than white light colonoscopy or narrow band imaging colonoscopy in hereditary nonpolyposis colorectal cancer screening.在遗传性非息肉病性结直肠癌筛查中,染色结肠镜检查比白光结肠镜检查或窄带成像结肠镜检查能检测出更多的腺瘤。
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Elastic scattering spectroscopy for the diagnosis of colonic lesions: initial results of a novel optical biopsy technique.用于结肠病变诊断的弹性散射光谱法:一种新型光学活检技术的初步结果
Gastrointest Endosc. 2006 Feb;63(2):257-61. doi: 10.1016/j.gie.2005.07.026.
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[Distal hyperplastic polyps as a marker for advanced neoplasm of the proximal colon. Our experience].[远端增生性息肉作为近端结肠高级别肿瘤的标志物。我们的经验]
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Serum insulin levels and the prevalence of adenomatous and hyperplastic polyps in the proximal colon.血清胰岛素水平与近端结肠腺瘤性息肉和增生性息肉的患病率
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[Correlation between hyperplastic and adenomatous polyps of the colon].[结肠增生性息肉与腺瘤性息肉之间的相关性]
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[The assessment of colonic polyps found via colonoscopy].[通过结肠镜检查发现的结肠息肉的评估]
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