Dalbo Vincent J, Roberts Michael D, Lockwood Chris M, Tucker Patrick S, Kreider Richard B, Kerksick Chad M
Applied Biochemistry and Molecular Physiology Laboratory, Department of Health & Exercise Science, University of Oklahoma, Norman, OK, USA.
Dyn Med. 2009 Dec 24;8:6. doi: 10.1186/1476-5918-8-6.
Creatine supplementation has been found to significantly increase muscle strength and hypertrophy in young adults (</= 35 yr) particularly when consumed in conjunction with a resistance training regime. Literature examining the efficacy of creatine supplementation in older adults (55-82 yr) suggests creatine to promote muscle strength and hypertrophy to a greater extent than resistance training alone. The following is a review of literature reporting on the effects of creatine supplementation on intramuscular high energy phosphates, skeletal muscle morphology and quality of life in older adults. Results suggest creatine supplementation to be a safe, inexpensive and effective nutritional intervention, particularly when consumed in conjunction with a resistance training regime, for slowing the rate of muscle wasting that is associated with aging. Physicians should strongly consider advising older adults to supplement with creatine and to begin a resistance training regime in an effort to enhance skeletal muscle strength and hypertrophy, resulting in enhanced quality of life.
已发现补充肌酸可显著增强年轻人（≤35岁）的肌肉力量并促进肌肉肥大，尤其是在与抗阻训练相结合时。有关补充肌酸对老年人（55 - 82岁）功效的文献表明，肌酸比单独进行抗阻训练更能有效促进肌肉力量和肥大。以下是一篇关于补充肌酸对老年人肌肉内高能磷酸盐、骨骼肌形态和生活质量影响的文献综述。结果表明，补充肌酸是一种安全、廉价且有效的营养干预措施，尤其是在与抗阻训练相结合时，可减缓与衰老相关的肌肉萎缩速度。医生应强烈建议老年人补充肌酸并开始抗阻训练，以增强骨骼肌力量和肥大，从而提高生活质量。
