Tecnobios Procreazione, Centre for Reproductive Health, Via Dante 15, I-40125 Bologna, Italy.
Reprod Biomed Online. 2009;19 Suppl 3:45-55. doi: 10.1016/s1472-6483(10)60283-0.
To date, several publications have focused their attention on a new method for observing spermatozoa called 'motile sperm organelle morphology examination' (MSOME), which enables the evaluation of the fine nuclear morphology of motile spermatozoa in real time at high magnification (>x6000). As a consequence, a new microinjection procedure called intracytoplasmic morphologically selected sperm injection (IMSI) has been developed. The aim of the present work is therefore to evaluate the efficacy of the IMSI technique in the light of the current literature, focusing attention on the potential clinical application of the selection of strictly morphologically normal spermatozoa in patients undergoing conventional intracytoplasmic sperm injection treatments. In addition, a brief analysis of preliminary data regarding the relationship between IMSI and assisted reproduction treatment outcome is presented.
迄今为止，已有多篇出版物关注一种新的精子观察方法，称为“运动精子细胞器形态检查”（MSOME），该方法可实时在高倍镜（>x6000）下评估运动精子的精细核形态。因此，一种新的称为胞质内形态选择精子注射（IMSI）的微注射程序已经开发出来。因此，本研究旨在根据现有文献评估 IMSI 技术的疗效，重点关注在常规胞质内精子注射治疗中选择严格形态正常精子的潜在临床应用。此外，还对 IMSI 与辅助生殖治疗结局之间关系的初步数据进行了简要分析。
