Department of Surgery, Jen-Ai Hospital-Tali, 483 DongRong Road, Tali City, Taichung, Taiwan, ROC.
World J Surg. 2010 Feb;34(2):303-8. doi: 10.1007/s00268-009-0271-4.
We inaugurated a clinical trial using laparoscopic gastric clipping to treat morbid obesity patients. We report the 2-year results.
Ten patients with morbid obesity underwent laparoscopic gastric clipping to promote weight loss. A novel metallic clip was applied to the outside wall of the upper fundus of the stomach by a laparoscopic technique. The clip allowed a restricted passage of meals through a mucosa tunnel 0.4-0.6 cm in diameter.
The body weight and feeding status of the patients were monitored periodically. Barium meal studies at 1 day and 2 years after the clipping were compared.
Ten patients (3 men, 7 women) with body weight of 117 +/- 18.2 kg (101.8-156.5) and body mass index (BMI) 43.4 +/- 5.2 (40-56) were included. The gastric clips were successfully applied laparoscopically in all patients. The operation time ranged from 65 to 210 minutes and showed a learning curve. The excess body weight loss was progressive and long lasting postoperatively. The mean BMI and percentage of excess body weight loss at the 2-year period was 32.01 +/- 4.89 kg/m(2) and 64.4%, respectively. The mean BMI 2 years after surgery was significantly decreased compared with that before surgery. Barium meal studies did not show significant sliding or migration of the clips at 2-year follow-up. No mortality or late complications occurred.
Our results indicate that laparoscopic gastric clipping is a safe, simple, and effective treatment for patients with morbid obesity.
我们启动了一项使用腹腔镜胃夹治疗病态肥胖患者的临床试验。我们报告了 2 年的结果。
10 例病态肥胖患者接受腹腔镜胃夹治疗以促进体重减轻。一种新型金属夹通过腹腔镜技术应用于胃上部外壁。夹子允许直径为 0.4-0.6 厘米的粘膜隧道限制通过餐食。
定期监测患者的体重和喂养情况。比较夹闭后 1 天和 2 年的钡餐研究。
10 例患者（3 名男性，7 名女性）体重为 117 ± 18.2kg（101.8-156.5），体重指数（BMI）为 43.4 ± 5.2（40-56）。所有患者均成功地进行了腹腔镜胃夹应用。手术时间从 65 分钟到 210 分钟不等，表现出学习曲线。术后超重体重持续下降且持久。2 年期间平均 BMI 和超重体重减轻百分比分别为 32.01 ± 4.89kg/m2和 64.4%。手术后 2 年的平均 BMI 与术前相比明显降低。钡餐研究在 2 年随访时未显示夹子有明显滑动或迁移。无死亡或迟发性并发症发生。
我们的结果表明，腹腔镜胃夹治疗病态肥胖患者是一种安全、简单、有效的治疗方法。
