Department of Nutrition, University of North Carolina Greensboro, Greensboro, NC 27412, USA.
J Steroid Biochem Mol Biol. 2010 Oct;122(1-3):65-73. doi: 10.1016/j.jsbmb.2009.12.005. Epub 2009 Dec 24.
In recent years, obesity and its associated health disorders and costs have increased. Accumulation of adipose tissue, or fat, in the intra-abdominal adipose depot is associated with an increased risk of developing cardiovascular problems, type-2 diabetes mellitus, certain cancers, and other disorders like the metabolic syndrome. Males and females differ in terms of how and where their body fat is stored, in their hormonal secretions, and in their neural responses to signals regulating weight and body fat distribution. Men and post-menopausal women accumulate more fat in their intra-abdominal depots than pre-menopausal women, resulting in a greater risk of developing complications associated with obesity. The goal of this review is to discuss the current literature on sexual dimorphisms in body weight regulation, adipose tissue accrual and deposition.
近年来，肥胖及其相关的健康问题和费用不断增加。在腹部脂肪库中积累的脂肪与患心血管问题、2 型糖尿病、某些癌症和其他代谢综合征等疾病的风险增加有关。男性和女性在身体脂肪储存的方式和位置、激素分泌以及对调节体重和体脂分布的信号的神经反应方面存在差异。男性和绝经后女性比绝经前女性在腹部脂肪库中积累更多的脂肪，导致与肥胖相关的并发症的风险增加。本综述的目的是讨论关于体重调节、脂肪组织积累和沉积的性别二态性的现有文献。
