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[西班牙马德里脑膜炎球菌感染的住院情况(1997 - 2005年)]

[Hospital admissions for meningococcal infections in Madrid, Spain (1997-2005)].

作者信息

Gil Prieto Ruth, Alvarez Morán José Luis, Portugal Pilar, San Román Montero Jesús, Alvaro Alejandro, Rivero Cuadrado Agustín

机构信息

Departamento de Ciencias de la Salud, Universidad Rey Juan Carlos, Alcorcón, Madrid, España.

出版信息

Med Clin (Barc). 2010 Apr 24;134(12):534-9. doi: 10.1016/j.medcli.2009.10.035. Epub 2009 Dec 29.

DOI:10.1016/j.medcli.2009.10.035
PMID:20036397
Abstract

BACKGROUND AND OBJECTIVES

Neisseria meningitidis infection causes an important morbidity and mortality in Spain. Our study aims to estimate the burden of hospital admissions for meningococcal infection in Spain during a nine-year period (1997-2005) by analyzing the Spanish hospital surveillance system.

METHODS

An epidemiological retrospective study was conducted. Data were obtained from the national surveillance system for hospital data (Conjunto Mínimo Básico de Datos) maintained by the Ministry of Health. Information about hospitalizations, age, length of stay in hospital, mortality and cost per patient was obtained.

RESULTS

There were 1137 hospital discharges for meningococcal disease (International Classification of Diseases 9th Clinical Modification: ICD 9 CM code 036 in any listed diagnosis) during the study period. Annual incidence was 2.41 cases per 100,000 individuals. Mortality rate and case-fatality rate were 0.19 cases per 100,000 population and 7.7%, respectively. The average length of hospitalization was 12 days. The youngest age group showed the highest hospitalizations incidence (24.42 hospitalizations per 100,000 population in those under 4 years of age) but the case-fatality rate was higher in the oldest group (11% in patients over 30 years). These hospitalizations imply an annual cost of 592,980 euro to the Madrid Health System.

CONCLUSIONS

Our study shows that meningococcal infection is still an important cause of hospital admissions and mortality in Madrid, resulting in a high cost to the Health Care System.

摘要

背景与目的

在西班牙,脑膜炎奈瑟菌感染导致了严重的发病率和死亡率。我们的研究旨在通过分析西班牙医院监测系统,估算1997年至2005年这九年期间西班牙脑膜炎球菌感染的住院负担。

方法

开展了一项流行病学回顾性研究。数据来自卫生部维护的国家医院数据监测系统(基本最小数据集)。获取了有关住院情况、年龄、住院时长、死亡率以及每位患者费用的信息。

结果

研究期间,有1137例因脑膜炎球菌病出院(国际疾病分类第九版临床修订本:任何列出的诊断中ICD 9 CM编码036)。年发病率为每10万人2.41例。死亡率和病死率分别为每10万人口0.19例和7.7%。平均住院时长为12天。最年轻年龄组的住院发病率最高(4岁以下人群中每10万人口有24.42例住院),但病死率在最年长组中更高(30岁以上患者中为11%)。这些住院病例给马德里卫生系统带来的年度成本为592,980欧元。

结论

我们的研究表明,脑膜炎球菌感染仍是马德里住院和死亡的重要原因,给医疗保健系统带来了高昂成本。

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