Roth M E, Grant-Kels J M, Ackerman A B, Elder D E, Friedman R J, Heilman E R, Maize J C, Sagebiel R W
Division of Dermatology, Brown University School of Medicine, Providence, Rhode Island.
Am J Dermatopathol. 1991 Feb;13(1):38-51. doi: 10.1097/00000372-199102000-00008.
The histopathologic criteria used in the diagnosis of dysplastic nevi have been a source of controversy, as has the clinical significance of these lesions. Several dermatopathologists noted for their work on dysplastic nevi were asked to contribute responses to questions regarding the architectural and cytological criteria used to classify a melanocytic nevus as dysplastic, the terminology used to describe these lesions, and the role of dysplastic nevi as precursors of melanoma. Although no consensus has been reached regarding the cytologic features required for diagnosis of dysplastic nevi, there is substantial agreement regarding the architectural features of these lesions.
用于诊断发育异常痣的组织病理学标准一直是争议的来源,这些病变的临床意义也是如此。几位以研究发育异常痣而闻名的皮肤病理学家被要求回答有关将黑素细胞痣分类为发育异常所使用的结构和细胞学标准、描述这些病变所使用的术语以及发育异常痣作为黑色素瘤前体的作用等问题。尽管对于诊断发育异常痣所需的细胞学特征尚未达成共识,但对于这些病变的结构特征存在大量共识。