Petrikas A Zh, Egorova V A, Ermilova K V
Stomatologiia (Mosk). 2009;88(5):24-6.
5 articaine preparations including besides 4% articaine with epinephrine 1:100 000 and 1:200 000, 4% articaine with epinephrine 1:400 000, 2% articaine 1:200 000 and articaine without a vasoconstrictor were investigated on 52 volunteers, dental students. It was established that new combinations of articaine with epinephrine had relatively high activity to anesthetize dental pulp which was comparable with classic agents but slightly inferior to them in all the criteria studied. Articaine without adrenaline had not practically induced pulpal analgesia.
对52名志愿者(牙科专业学生)使用了5种阿替卡因制剂进行研究,其中包括4%阿替卡因与1:100 000和1:200 000肾上腺素的组合、4%阿替卡因与1:400 000肾上腺素的组合、2%阿替卡因与1:200 000肾上腺素的组合以及不含血管收缩剂的阿替卡因。结果表明,阿替卡因与肾上腺素的新组合对牙髓麻醉具有较高活性,与传统制剂相当,但在所有研究标准上略逊一筹。不含肾上腺素的阿替卡因几乎未引起牙髓镇痛。