Wilson S E, Klyce S D
Louisiana State University Medical Center School of Medicine, New Orleans.
Arch Ophthalmol. 1991 Mar;109(3):349-53. doi: 10.1001/archopht.1991.01080030051037.
Quantitative descriptors of corneal topography determined by computerized algorithm and designed to augment the information derived from topographic maps were evaluated in a clinical study. The surface regularity index, a measure of central corneal optical quality, was highly correlated with best spectacle-corrected visual acuity (rho = 0.80, P less than .001). The relatively low correlation between the surface asymmetry index, a measure of central corneal asymmetry, and best spectacle-corrected visual acuity (rho = 0.62, P less than .005) suggests that corneal symmetry is a lesser but still important determinant of the optical performance of the anterior corneal surface. There was also a high correlation between factors determined from computer-generated orthogonal simulated keratometer values and clinical keratometry values (mean corneal power, total corneal cylinder, and the location of the steepest corneal meridian). The information derived from these algorithms has both clinical and research applications and can be incorporated into computer-assisted topographic analysis systems.
在一项临床研究中，对通过计算机算法确定的、旨在增强从地形图中获取的信息的角膜地形图定量描述符进行了评估。表面规则性指数是衡量中央角膜光学质量的指标，与最佳眼镜矫正视力高度相关（rho = 0.80，P <.001）。表面不对称指数是衡量中央角膜不对称性的指标，与最佳眼镜矫正视力之间的相关性相对较低（rho = 0.62，P <.005），这表明角膜对称性对角膜前表面光学性能的决定作用较小但仍然很重要。由计算机生成的正交模拟角膜曲率计值确定的因素与临床角膜曲率计值（平均角膜屈光力、总角膜散光和最陡角膜子午线的位置）之间也存在高度相关性。从这些算法中获得的信息具有临床和研究应用价值，并且可以纳入计算机辅助地形图分析系统。
