Wei Yinjuan, Xu Lingxiao, Song Hui
Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Clinical College of Ophthalmology, Tianjin Medical University, Tianjin 300020, P.R. China.
Exp Ther Med. 2017 Aug;14(2):1626-1632. doi: 10.3892/etm.2017.4675. Epub 2017 Jun 26.
The aim of the present study was to evaluate the effects of femtosecond laser-assisted cataract surgery (FLACS) and phacoemulsification on corneal biomechanics using corneal visualization Scheimpflug technology. The medical records of 50 eyes from 50 patients who received phacoemulsification and intraocular lens implantation because of age-related factors between June 2014 and September 2014 were retrospectively analyzed. FLACS was used in 12 eyes (FLACS group), and conventional phacoemulsification in 38 eyes (PHACO group). The evaluation of corneal biomechanical parameters included the first/second applanation time (A-time1/A-time2), the first/second applanation length (A-length1/A-length2), corneal velocity during the first/second applanation moment (Vin/Vout), highest concavity time, highest concavity-radius (HC-radius), peak distance (PD), deformation amplitude (DA), central corneal thickness (CCT), and intraocular pressure (IOP). The differences in A-length1/A-length2, IOP, CCT, PD, and DA were significant in the PHACO group between those before, 1 week after, and 1 month after surgery. No significant differences in corneal biomechanical parameters were found between those at 1 month after surgery and before surgery. There were significant differences in IOP and CCT in the FLACS group between those before, 1 week after, and 1 month after surgery. There were no significant differences in the other corneal biomechanical parameters. No significant differences were found in corneal biomechanical parameters between those 1 month after surgery and before surgery. There were significant differences in A-length1/A-length2, CCT, PD, and DA between the two groups at 1 week after surgery. There were no significant differences in corneal biomechanical parameters between the two groups at 1 month after surgery. In conclusion, the effect of FLACS on corneal biomechanics is smaller than that of phacoemulsification. The corneal biomechanical parameters are restored to preoperative levels with the healing of the incision, and the reduction of swelling of the tissue near the incision.
本研究的目的是使用角膜可视化Scheimpflug技术评估飞秒激光辅助白内障手术（FLACS）和超声乳化术对角膜生物力学的影响。回顾性分析了2014年6月至2014年9月期间因年龄相关因素接受超声乳化术和人工晶状体植入术的50例患者的50只眼的病历。12只眼采用FLACS（FLACS组），38只眼采用传统超声乳化术（PHACO组）。角膜生物力学参数的评估包括第一次/第二次压平时间（A-time1/A-time2）、第一次/第二次压平长度（A-length1/A-length2）、第一次/第二次压平瞬间的角膜速度（Vin/Vout）、最高凹陷时间、最高凹陷半径（HC-radius）、峰值距离（PD）、变形幅度（DA）、中央角膜厚度（CCT）和眼内压（IOP）。PHACO组手术前、术后1周和术后1个月的A-length1/A-length2、IOP、CCT、PD和DA存在显著差异。术后1个月与术前相比，角膜生物力学参数无显著差异。FLACS组手术前、术后1周和术后1个月的IOP和CCT存在显著差异。其他角膜生物力学参数无显著差异。术后1个月与术前相比，角膜生物力学参数无显著差异。术后1周两组之间的A-length1/A-length2、CCT、PD和DA存在显著差异。术后1个月两组之间的角膜生物力学参数无显著差异。总之，FLACS对角膜生物力学的影响小于超声乳化术。随着切口愈合以及切口附近组织肿胀的减轻，角膜生物力学参数恢复到术前水平。
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