Department of Population Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA.
Nat Rev Microbiol. 2010 Feb;8(2):139-48. doi: 10.1038/nrmicro2268. Epub 2009 Dec 30.
In recent decades, theory addressing the processes that underlie the dynamics of infectious diseases has progressed considerably. Unfortunately, the availability of empirical data to evaluate these theories has not grown at the same pace. Although laboratory animals have been widely used as models at the organism level, they have been less appropriate for addressing issues at the population level. However, farm animal populations can provide empirical models to study infectious diseases at the population level.
近几十年来,关于传染病动力学背后过程的理论研究取得了相当大的进展。不幸的是,用于评估这些理论的经验数据并没有以同样的速度增长。虽然实验室动物在机体水平上被广泛用作模型,但它们不太适合解决群体水平上的问题。然而,农场动物种群可以提供经验模型来研究群体水平上的传染病。