Institute for Toxicology & Cancer Risk Factors, German Cancer Research Center, Heidelberg, Germany.
J Med Food. 2009 Dec;12(6):1316-20. doi: 10.1089/jmf.2008.0211.
Consumption of certain fruits and vegetables is now widely associated with chemoprevention of degenerative diseases like cancer and cardiovacsular disorders because of their antioxidant components. Polyphenols, a heterogeneous group of compounds, are one of these constituents. Hibiscus esculentus L. (Family Malvaceae), commonly referred to as okro, okra, or lady's finger, is an important component of diet in Nigeria and other countries in sub-Saharan Africa. In this article, we describe the polyphenol composition and antioxidant potential of H. esculentus of Nigerian origin. Quercetin glucoside (quercetrin) and an unidentified flavonoid were detected. In vitro antioxidant assay of methanol extract of the fruits showed potent antioxidant/radical scavenging activities with 50% inhibitory concentration values of 25 and 43 microL when analyzed by the xanthine oxidase and 2-deoxyguanosine methods, respectively. These data suggest that H. esculentus, popular especially during the rainy season in Nigeria and many tropical West, Central, and Eastern African countries, is a good contributor to the antioxidant status and disease chemoprevention of people in these countries.
由于其抗氧化成分,某些水果和蔬菜的消费现在与癌症和心血管疾病等退行性疾病的化学预防广泛相关。多酚是这些成分之一,是一组异构化合物。Hibiscus esculentus L.(锦葵科),通常称为 okro、okra 或 lady's finger,是尼日利亚和撒哈拉以南非洲其他国家饮食的重要组成部分。在本文中,我们描述了源自尼日利亚的 H. esculentus 的多酚组成和抗氧化潜力。检测到槲皮素葡萄糖苷(槲皮素)和一种未鉴定的类黄酮。水果甲醇提取物的体外抗氧化分析表明,当用黄嘌呤氧化酶和 2-脱氧鸟苷方法分析时,具有很强的抗氧化/自由基清除活性,50%抑制浓度值分别为 25 和 43 μL。这些数据表明,H. esculentus 在尼日利亚和许多热带西部、中部和东部非洲国家的雨季特别受欢迎,是这些国家人们抗氧化状态和疾病化学预防的良好贡献者。