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粘红酵母致多发性骨髓瘤患者导管相关真菌血症

Rhodotorula mucilaginosa catheter-related fungaemia in a patient with multiple myeloma.

出版信息

Mycoses. 2011 Jul;54(4):e214-6. doi: 10.1111/j.1439-0507.2009.01816.x. Epub 2009 Dec 23.

DOI:10.1111/j.1439-0507.2009.01816.x
PMID:20041994
Abstract

To date, there have been several case reports of Rhodotorula infection in haematological patients, but none affecting patients with multiple myeloma (MM). We describe a 54-year-old man with MM receiving prophylaxis with fluconazole who was using a subclavian Port-A-Cath and presented two episodes of fungaemia caused by Rhodotorula mucilaginosa. The first episode was resolved with oral itraconazole and neutropenia recovery. During the second episode, caspofungin was administered without success; however, liposomal amphotericin B and catheter withdrawal resolved the fungaemia. As far as we know, this is the first case reported of R. mucilaginosa fungaemia in a patient with MM.

摘要

迄今为止,已有几例血液系统疾病患者感染红酵母的病例报告,但均未影响多发性骨髓瘤(MM)患者。我们描述了一位 54 岁男性,患有 MM,接受氟康唑预防治疗,使用锁骨下 Port-A-Cath,出现了两次由粘红酵母引起的真菌血症。第一次发作经口服伊曲康唑和中性粒细胞恢复而解决。第二次发作时,给予卡泊芬净治疗无效;然而,脂质体两性霉素 B 和导管拔出解决了真菌血症。据我们所知,这是首例 MM 患者粘红酵母血症的病例报告。

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