Department of medicine, Teikyo University, 2-11-1 Kaga, Itabashi-ku, Tokyo, Japan.
Department of laboratory medicine, Teikyo University Hospital, Tokyo, Japan.
J Mycol Med. 2018 Jun;28(2):393-395. doi: 10.1016/j.mycmed.2018.04.001. Epub 2018 Apr 14.
Rhodotorula species are environmental basidiomycete yeasts that have emerged as a cause of fungemia in immunocompromised hosts. The insertion of a central venous catheter was identified as a major risk factor for Rhodotorula fungemia. Few cases reports have reported (1→3)-β-D-glucan testing at the onset of Rhodotorula mucilaginosa fungemia. We report a case of catheter-related bloodstream infection due to R. mucilaginosa. Serum β-D-glucan level was normal at the onset of the bloodstream infection. It took 5 days to culture the isolate. The patient's fever persisted after empiric treatment with micafungin, and a switch to oral voriconazole immediately resolved the fungemia.
红酵母属是一种环境担子菌酵母菌，已成为免疫功能低下宿主中真菌血症的病因。中央静脉导管的插入被确定为红酵母属真菌血症的一个主要危险因素。少数病例报告在黏红酵母属真菌血症开始时进行了（1→3）-β-D-葡聚糖检测。我们报告了一例导管相关血流感染，由黏红酵母属引起。血流感染开始时血清β-D-葡聚糖水平正常。培养分离株需要 5 天时间。经验性米卡芬净治疗后，患者的发热持续存在，立即改用口服伏立康唑即可解决真菌血症。
