纳米技术与可植入生物传感器的协同作用：综述。
Emerging synergy between nanotechnology and implantable biosensors: a review.
机构信息
Nanomaterials Optoelectronics Laboratory, Polymer Program, Institute of Materials Science, University of Connecticut, Storrs, CT 06269, USA.
出版信息
Biosens Bioelectron. 2010 Mar 15;25(7):1553-65. doi: 10.1016/j.bios.2009.12.001. Epub 2009 Dec 11.
Abstract
The development of implantable biosensors for continuous monitoring of metabolites is an area of sustained scientific and technological interests. On the other hand, nanotechnology, a discipline which deals with the properties of materials at the nanoscale, is developing as a potent tool to enhance the performance of these biosensors. This article reviews the current state of implantable biosensors, highlighting the synergy between nanotechnology and sensor performance. Emphasis is placed on the electrochemical method of detection in light of its widespread usage and substantial nanotechnology based improvements in various aspects of electrochemical biosensor performance. Finally, issues regarding toxicity and biocompatibility of nanomaterials, along with future prospects for the application of nanotechnology in implantable biosensors, are discussed.
摘要
可植入生物传感器用于连续监测代谢物的开发是一个持续的科学和技术兴趣领域。另一方面，纳米技术是一门研究纳米尺度下材料性质的学科，它正在发展成为增强这些生物传感器性能的有力工具。本文综述了可植入生物传感器的现状，强调了纳米技术与传感器性能之间的协同作用。鉴于电化学检测方法在电化学生物传感器性能的各个方面的广泛应用和实质性的纳米技术改进，本文重点介绍了电化学检测方法。最后，讨论了纳米材料的毒性和生物相容性问题，以及纳米技术在可植入生物传感器中的应用前景。
相似文献
1
Emerging synergy between nanotechnology and implantable biosensors: a review.纳米技术与可植入生物传感器的协同作用：综述。
Biosens Bioelectron. 2010 Mar 15;25(7):1553-65. doi: 10.1016/j.bios.2009.12.001. Epub 2009 Dec 11.
2
Biosensors for real-time in vivo measurements.用于实时体内测量的生物传感器。
Biosens Bioelectron. 2005 Jun 15;20(12):2388-403. doi: 10.1016/j.bios.2004.12.003. Epub 2005 Jan 15.
3
Ion sensitive field effect transducer-based biosensors.基于离子敏感场效应传感器的生物传感器。
Biotechnol Adv. 2003 Sep;21(6):527-34. doi: 10.1016/s0734-9750(03)00103-4.
4
Nanotechnology for implantable sensors: carbon nanotubes and graphene in medicine.纳米技术在植入式传感器中的应用：碳纳米管和石墨烯在医学中的应用。
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2013 May-Jun;5(3):233-49. doi: 10.1002/wnan.1213. Epub 2013 Feb 28.
5
Recent advances in nanomaterial-based biosensors for antibiotics detection.基于纳米材料的抗生素检测生物传感器的最新进展。
Biosens Bioelectron. 2017 May 15;91:504-514. doi: 10.1016/j.bios.2017.01.007. Epub 2017 Jan 5.
6
Biosensing: new probes offer much faster results.生物传感：新型探针可提供更快的检测结果。
Nat Nanotechnol. 2007 Dec;2(12):746-8. doi: 10.1038/nnano.2007.398.
7
Current trends in nanomaterial embedded field effect transistor-based biosensor.基于纳米材料嵌入场效应晶体管的生物传感器的当前发展趋势。
Biosens Bioelectron. 2015 Dec 15;74:731-43. doi: 10.1016/j.bios.2015.07.030. Epub 2015 Jul 15.
8
Introduction to the special issue on "State-of-the-Art Sensor Technology in Japan 2012".《2012年日本传感器技术现状》特刊引言
Sensors (Basel). 2014 Jun 23;14(6):11045-8. doi: 10.3390/s140611045.
9
[Research Progress of Implantable Biosensors for Continuous Glucose Monitoring].用于连续血糖监测的可植入生物传感器的研究进展
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2016 Oct;33(5):991-7.
10
Towards development of chemosensors and biosensors with metal-oxide-based nanowires or nanotubes.迈向基于金属氧化物纳米线或纳米管的化学传感器和生物传感器的开发。
Biosens Bioelectron. 2008 Oct 15;24(2):167-77. doi: 10.1016/j.bios.2008.04.014. Epub 2008 Apr 26.
引用本文的文献
1
Biosensors, Artificial Intelligence Biosensors, False Results and Novel Future Perspectives.生物传感器、人工智能生物传感器、错误结果及新的未来展望。
Diagnostics (Basel). 2025 Apr 18;15(8):1037. doi: 10.3390/diagnostics15081037.
2
Glucose-based biofuel cells and their applications in medical implants: A review.基于葡萄糖的生物燃料电池及其在医疗植入物中的应用：综述
Heliyon. 2024 Jun 25;10(13):e33615. doi: 10.1016/j.heliyon.2024.e33615. eCollection 2024 Jul 15.
3
Advances in Wireless, Batteryless, Implantable Electronics for Real-Time, Continuous Physiological Monitoring.用于实时、连续生理监测的无线、无电池植入式电子设备的进展。
Nanomicro Lett. 2023 Dec 15;16(1):52. doi: 10.1007/s40820-023-01272-6.
4
Recent Progress in Biomedical Sensors Based on Conducting Polymer Hydrogels.基于导电聚合物水凝胶的生物医学传感器的最新进展。
ACS Appl Bio Mater. 2023 May 15;6(5):1720-1741. doi: 10.1021/acsabm.3c00139. Epub 2023 Apr 28.
5
Highly Miniaturized, Low-Power CMOS ASIC Chip for Long-Term Continuous Glucose Monitoring.高度微型化、低功耗 CMOS 专用集成电路芯片，用于长期连续血糖监测。
J Diabetes Sci Technol. 2024 Sep;18(5):1179-1184. doi: 10.1177/19322968231153419. Epub 2023 Feb 11.
6
Nanomaterial-Based Electrochemical Nanodiagnostics for Human and Gut Metabolites Diagnostics: Recent Advances and Challenges.基于纳米材料的电化学纳米诊断在人类和肠道代谢物诊断中的应用：最新进展与挑战。
Biosensors (Basel). 2022 Sep 6;12(9):733. doi: 10.3390/bios12090733.
7
Biosensor-Integrated Drug Delivery Systems as New Materials for Biomedical Applications.生物传感器集成药物输送系统作为生物医学应用的新材料。
Biomolecules. 2022 Aug 29;12(9):1198. doi: 10.3390/biom12091198.
8
Advances in Nanomaterial-based Biosensors for Determination of Glycated Hemoglobin.用于测定糖化血红蛋白的纳米材料基生物传感器的进展
Curr Top Med Chem. 2022;22(27):2261-2281. doi: 10.2174/1568026622666220915114646.
9
Clinically oriented Alzheimer's biosensors: expanding the horizons towards point-of-care diagnostics and beyond.临床导向的阿尔茨海默病生物传感器：拓展即时诊断及其他领域的视野
RSC Adv. 2021 Jun 8;11(33):20403-20422. doi: 10.1039/d1ra01553b. eCollection 2021 Jun 3.
10
Nanomaterials and metal-organic frameworks for biosensing applications of mutations of the emerging viruses.用于新兴病毒突变的生物传感应用的纳米材料和金属有机骨架。
Anal Biochem. 2022 Jul 1;648:114680. doi: 10.1016/j.ab.2022.114680. Epub 2022 Apr 14.
本文引用的文献
1
Electrical Communication between Electrodes and Enzymes Mediated by Redox Hydrogels.氧化还原水凝胶介导的电极与酶之间的电通信。
Anal Chem. 1996 Dec 1;68(23):4186-93. doi: 10.1021/ac960170n.
2
Layer-by-layer assembled semipermeable membrane for amperometric glucose sensors.用于安培型葡萄糖传感器的逐层组装半透膜
J Diabetes Sci Technol. 2007 Mar;1(2):193-200. doi: 10.1177/193229680700100209.
3
Immobilization techniques to avoid enzyme loss from oxidase-based biosensors: a one-year study.避免基于氧化酶的生物传感器中酶损失的固定化技术：一项为期一年的研究。
J Diabetes Sci Technol. 2007 Jan;1(1):18-27. doi: 10.1177/193229680700100104.
4
Controlling acute inflammation with fast releasing dexamethasone-PLGA microsphere/pva hydrogel composites for implantable devices.用用于可植入装置的快速释放地塞米松 - PLGA微球/聚乙烯醇水凝胶复合材料控制急性炎症。
J Diabetes Sci Technol. 2007 Jan;1(1):8-17. doi: 10.1177/193229680700100103.
5
A review of the development of a vehicle for localized and controlled drug delivery for implantable biosensors.用于可植入生物传感器的局部和可控药物递送载体的发展综述。
J Diabetes Sci Technol. 2008 Nov;2(6):1016-29. doi: 10.1177/193229680800200611.
6
A review of the biocompatibility of implantable devices: current challenges to overcome foreign body response.植入式设备的生物相容性综述：克服异物反应的当前挑战
J Diabetes Sci Technol. 2008 Nov;2(6):1003-15. doi: 10.1177/193229680800200610.
7
Quantum phenomena in Nanotechnology.纳米技术中的量子现象。
Nanotechnology. 2009 Oct 28;20(43):430205. doi: 10.1088/0957-4484/20/43/430205. Epub 2009 Oct 2.
8
Electrical contacting of redox enzymes by means of oligoaniline-cross-linked enzyme/carbon nanotube composites.通过聚邻苯二胺交联的酶/碳纳米管复合材料实现氧化还原酶的电接触。
Langmuir. 2009 Dec 15;25(24):13978-83. doi: 10.1021/la902074w.
9
Application of quantum chemistry to nanotechnology: electron and spin transport in molecular devices.量子化学在纳米技术中的应用：分子器件中的电子与自旋输运
Chem Soc Rev. 2009 Aug;38(8):2319-33. doi: 10.1039/b820003c. Epub 2009 Apr 15.
10
Organic photodiodes for biosensor miniaturization.用于生物传感器小型化的有机光电二极管。
Anal Chem. 2009 May 1;81(9):3455-61. doi: 10.1021/ac8027323.
Zotero 插件