School of Biosystems Engineering and Food Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, PR China.
School of Biosystems Engineering and Food Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, PR China.
Biosens Bioelectron. 2017 May 15;91:504-514. doi: 10.1016/j.bios.2017.01.007. Epub 2017 Jan 5.
Antibiotics are able to be accumulated in human body by food chain and may induce severe influence to human health and safety. Hence, the development of sensitive and simple methods for rapid evaluation of antibiotic levels is highly desirable. Nanomaterials with excellent electronic, optical, mechanical, and thermal properties have been recognized as one of the most promising materials for opening new gates in the development of next-generation biosensors. This review highlights the current advances in the nanomaterial-based biosensors for antibiotics detection. Different kinds of nanomaterials including carbon nanomaterials, metal nanomaterials, magnetic nanoparticles, up-conversion nanoparticles, and quantum dots have been applied to the construction of biosensors with two main signal-transducing mechanisms, i.e. optical and electrochemical. Furthermore, the current challenges and future prospects in this field are also included to provide an overview for future research directions.
抗生素可通过食物链在人体内蓄积，可能对人类健康和安全产生严重影响。因此，开发用于快速评估抗生素水平的灵敏而简单的方法是非常需要的。具有优异的电子、光学、机械和热性能的纳米材料已被认为是为开发下一代生物传感器开辟新途径的最有前途的材料之一。本综述重点介绍了基于纳米材料的抗生素检测生物传感器的最新进展。不同种类的纳米材料，包括碳纳米材料、金属纳米材料、磁性纳米粒子、上转换纳米粒子和量子点，已被应用于两种主要信号转导机制（即光学和电化学）的生物传感器的构建中。此外，还包括该领域目前面临的挑战和未来展望，为未来的研究方向提供了全面的概述。
