Departments of Neuroscience, Neurology and Rehabilitation Medicine, Uppsala University Hospital, Uppsala, Sweden.
Stroke. 2010 Feb;41(2):319-24. doi: 10.1161/STROKEAHA.109.558619. Epub 2009 Dec 31.
The prevalence of spasticity after first-ever stroke is approximately 20%, but there are no health economic studies on costs associated with spasticity after stroke. The objective of our study was to estimate direct costs of stroke with spasticity for patients surviving up to 1 year after the stroke event in comparison to costs of stroke without spasticity.
A representative sample of patients with first-ever stroke hospitalized at Uppsala University Hospital was eligible for our cross-sectional survey. All direct costs during 1 year were identified for each patient, including costs for hospitalization (acute and rehabilitation), primary health care, medication, and costs for municipality services. Swedish currency was converted to Purchasing Power Parities US dollar (PPP$).
Median age (interquartile range) was 73 years (18), and the proportion of women was 48%. The majority of the direct costs (78%) was associated with hospitalization, whereas 20% was associated with municipality services during 1 year after a first-ever stroke. Only 1% of all direct costs were related to primary health care and 1% to medication. The level of costs for patients with stroke was correlated with the presence of spasticity as measured with the modified Ashworth scale (r(s)=0.524) and with the degree of disability as measured with modified Rankin Scale (r(s)=0.624). The mean (median, interquartile range) direct cost for stroke patients with spasticity was PPP$ 84,195 (72,116, 53,707) compared with PPP$ 21,842 (12,385, 17,484) for patients with stroke without spasticity (P<0.001).
Direct costs for 12-month stroke survivors are 4 times higher than direct costs for patients with stroke without spasticity during the first year after the event.
首次中风后痉挛的患病率约为 20%,但尚无与中风后痉挛相关成本的健康经济学研究。本研究旨在评估中风后痉挛患者在中风事件后 1 年内的直接成本,并与无痉挛的中风患者的成本进行比较。
我们的横断面调查纳入了乌普萨拉大学医院首次住院的中风患者的代表性样本。为每位患者确定了 1 年内的所有直接费用,包括住院(急性和康复)、初级保健、药物和市政服务费用。瑞典货币已转换为购买力平价美元(PPP$)。
中位年龄(四分位间距)为 73 岁(18 岁),女性比例为 48%。大多数直接费用(78%)与住院有关,而首次中风后 1 年内与市政服务相关的直接费用占 20%。所有直接费用中仅有 1%与初级保健有关,1%与药物有关。中风患者的费用水平与改良 Ashworth 量表(r(s)=0.524)测量的痉挛存在以及改良 Rankin 量表(r(s)=0.624)测量的残疾程度相关。痉挛组中风患者的平均(中位数,四分位间距)直接费用为 PPP$84195(72116,53707),而无痉挛组中风患者的直接费用为 PPP$21842(12385,17484)(P<0.001)。
在中风事件发生后的 12 个月内,痉挛中风幸存者的直接成本是无痉挛中风患者的 4 倍。